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    LRP4 LDL receptor related protein 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 714038, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LRP4provided by VGNC
    Official Full Name
    LDL receptor related protein 4provided by VGNC
    Primary source
    VGNC:VGNC:74445
    See related
    Ensembl:ENSMMUG00000013100
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LRP4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (18845073..18905807)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (19112539..19174134)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene centriolar satellite-associated tubulin polyglutamylase complex regulator 1 Neighboring gene translation machinery-associated protein 7 pseudogene Neighboring gene ATPase Asna1 pseudogene Neighboring gene cytoskeleton associated protein 5 Neighboring gene small nucleolar RNA SNORD67 Neighboring gene coagulation factor II, thrombin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    low-density lipoprotein receptor-related protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      18845073..18905807
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015114355.2 → XP_014969841.2  low-density lipoprotein receptor-related protein 4

      UniProtKB/TrEMBL
      F6SZP3, H9FUD8, H9YVU0
      Related
      ENSMMUP00000037130.3, ENSMMUT00000044124.3
      Conserved Domains (9) summary
      smart00192
      Location:311 → 343
      LDLa; Low-density lipoprotein receptor domain class A
      smart00135
      Location:505 → 545
      LY; Low-density lipoprotein-receptor YWTD domain
      smart00179
      Location:395 → 434
      EGF_CA; Calcium-binding EGF-like domain
      cd00112
      Location:270 → 304
      LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
      cd05819
      Location:1085 → 1123
      NHL; NHL repeat [structural motif]
      pfam00058
      Location:1179 → 1219
      Ldl_recept_b; Low-density lipoprotein receptor repeat class B
      cl18310
      Location:1085 → 1277
      NHL; NHL repeat unit of beta-propeller proteins
      pfam00057
      Location:70 → 105
      Ldl_recept_a; Low-density lipoprotein receptor domain class A
      pfam14670
      Location:1313 → 1348
      FXa_inhibition; Coagulation Factor Xa inhibitory site
    Nucleotide Protein
    Heading Accession and Version

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