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    RANGAP1 Ran GTPase activating protein 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710698, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RANGAP1provided by VGNC
    Official Full Name
    Ran GTPase activating protein 1provided by VGNC
    Primary source
    VGNC:VGNC:76656
    See related
    Ensembl:ENSMMUG00000014166
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RANGAP1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (10210592..10264361)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (83318157..83360320, complement)

    Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114670350 Neighboring gene uncharacterized LOC114670351 Neighboring gene zinc finger CCCH-type containing 7B Neighboring gene chondroadherin like Neighboring gene L3MBTL histone methyl-lysine binding protein 2 Neighboring gene uncharacterized LOC114670352

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleocytoplasmic transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ran GTPase-activating protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041763.1 Reference Mmul_10 Primary Assembly

      Range
      10210592..10264361
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028827664.1 → XP_028683497.1  ran GTPase-activating protein 1 isoform X5

      UniProtKB/TrEMBL
      F6XVQ7, G7N3Y6
      Conserved Domains (3) summary
      cd00116
      Location:21 → 360
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:51 → 81
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:406 → 584
      RanGAP1_C; RanGAP1 C-terminal domain

    2. XM_028827660.1 → XP_028683493.1  ran GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      G7N3Y6
      Conserved Domains (3) summary
      cd00116
      Location:76 → 415
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:106 → 136
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:463 → 697
      RanGAP1_C; RanGAP1 C-terminal domain

    3. XM_015150453.2 → XP_015005939.1  ran GTPase-activating protein 1 isoform X4

      UniProtKB/TrEMBL
      G7N3Y6
      Conserved Domains (3) summary
      cd00116
      Location:76 → 415
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:106 → 136
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:460 → 639
      RanGAP1_C; RanGAP1 C-terminal domain

    4. XM_015150456.2 → XP_015005942.1  ran GTPase-activating protein 1 isoform X6

      Conserved Domains (3) summary
      cd00116
      Location:76 → 415
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:106 → 136
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:460 → 514
      RanGAP1_C; RanGAP1 C-terminal domain

    5. XM_015150454.2 → XP_015005940.1  ran GTPase-activating protein 1 isoform X5

      UniProtKB/TrEMBL
      F6XVQ7, G7N3Y6
      Related
      ENSMMUP00000036977.3, ENSMMUT00000043975.3
      Conserved Domains (3) summary
      cd00116
      Location:21 → 360
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:51 → 81
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:406 → 584
      RanGAP1_C; RanGAP1 C-terminal domain

    6. XM_028827662.1 → XP_028683495.1  ran GTPase-activating protein 1 isoform X3

      UniProtKB/TrEMBL
      G7N3Y6
      Conserved Domains (3) summary
      cd00116
      Location:21 → 360
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:51 → 81
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:406 → 642
      RanGAP1_C; RanGAP1 C-terminal domain

    7. XM_028827661.1 → XP_028683494.1  ran GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      F7AMC6
      Related
      ENSMMUP00000018608.4, ENSMMUT00000019880.4
      Conserved Domains (3) summary
      cd00116
      Location:62 → 401
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:92 → 122
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:447 → 683
      RanGAP1_C; RanGAP1 C-terminal domain

    8. XM_028827663.1 → XP_028683496.1  ran GTPase-activating protein 1 isoform X3

      UniProtKB/TrEMBL
      G7N3Y6
      Conserved Domains (3) summary
      cd00116
      Location:21 → 360
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:51 → 81
      LRR_RI; leucine-rich repeat [structural motif]
      pfam07834
      Location:406 → 642
      RanGAP1_C; RanGAP1 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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