U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PARP8 poly(ADP-ribose) polymerase family member 8 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702637, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PARP8provided by VGNC
    Official Full Name
    poly(ADP-ribose) polymerase family member 8provided by VGNC
    Primary source
    VGNC:VGNC:84477
    See related
    Ensembl:ENSMMUG00000013841
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PARP8 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (48848442..49038905)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (51415576..51605869)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene U6 snRNA-associated Sm-like protein LSm5 Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene uncharacterized LOC106998765 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum tubular network IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intracellular anatomical structure IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nuclear envelope IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    poly [ADP-ribose] polymerase 8; protein mono-ADP-ribosyltransferase PARP8
    XP_001093952.1
    XP_014995548.2
    XP_014995550.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      48848442..49038905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001093952.4 → XP_001093952.1  protein mono-ADP-ribosyltransferase PARP8 isoform X2

      See identical proteins and their annotated locations for XP_001093952.1

      UniProtKB/TrEMBL
      F7HS77
      Related
      ENSMMUP00000034749.3, ENSMMUT00000041734.3
      Conserved Domains (1) summary
      cd01341
      Location:694 → 818
      ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...

    2. XM_015140064.2 → XP_014995550.1  protein mono-ADP-ribosyltransferase PARP8 isoform X1

      UniProtKB/TrEMBL
      F6SYG6, F7HS77
      Related
      ENSMMUP00000018192.4, ENSMMUT00000019426.4
      Conserved Domains (1) summary
      cd01341
      Location:734 → 858
      ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...

    3. XM_015140062.2 → XP_014995548.2  protein mono-ADP-ribosyltransferase PARP8 isoform X3

      UniProtKB/TrEMBL
      F7HS77
      Conserved Domains (1) summary
      cd01341
      Location:693 → 817
      ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.