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    STAT3 signal transducer and activator of transcription 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574128, updated on 17-Aug-2024

    Summary

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    Official Symbol
    STAT3provided by VGNC
    Official Full Name
    signal transducer and activator of transcription 3provided by VGNC
    Primary source
    VGNC:VGNC:77906
    See related
    Ensembl:ENSMMUG00000010707
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See STAT3 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (53439266..53524562, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (48164014..48253145, complement)

    Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene signal transducer and activator of transcription 5B Neighboring gene signal transducer and activator of transcription 5A Neighboring gene caveolae associated protein 1 Neighboring gene U7 small nuclear RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in leptin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    signal transducer and activator of transcription 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041769.1 Reference Mmul_10 Primary Assembly

      Range
      53439266..53524562 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028836496.1 → XP_028692329.1  signal transducer and activator of transcription 3 isoform X6

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:649 → 809
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:97 → 215
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:234 → 413
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:416 → 579
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    2. XM_028836500.1 → XP_028692333.1  signal transducer and activator of transcription 3 isoform X10

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:649 → 810
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:97 → 215
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:234 → 413
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:416 → 579
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    3. XM_028836499.1 → XP_028692332.1  signal transducer and activator of transcription 3 isoform X9

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:658 → 818
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:97 → 215
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:234 → 422
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:425 → 588
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    4. XM_028836493.1 → XP_028692326.1  signal transducer and activator of transcription 3 isoform X3

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:658 → 818
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:97 → 215
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:234 → 422
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:425 → 588
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    5. XM_028836498.1 → XP_028692331.1  signal transducer and activator of transcription 3 isoform X8

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:658 → 819
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:97 → 215
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:234 → 422
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:425 → 588
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    6. XM_028836491.1 → XP_028692324.1  signal transducer and activator of transcription 3 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:658 → 819
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:97 → 215
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:234 → 422
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:425 → 588
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    7. XM_028836503.1 → XP_028692336.1  signal transducer and activator of transcription 3 isoform X13

      UniProtKB/TrEMBL
      G7NIL1, H9FYY2
      Conserved Domains (4) summary
      cd10374
      Location:554 → 715
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 318
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:321 → 484
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    8. XM_028836502.1 → XP_028692335.1  signal transducer and activator of transcription 3 isoform X12

      UniProtKB/TrEMBL
      G7NIL1, H9FYX9
      Conserved Domains (4) summary
      cd10374
      Location:554 → 715
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 318
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:321 → 484
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    9. XM_028836497.1 → XP_028692330.1  signal transducer and activator of transcription 3 isoform X7

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:648 → 808
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:96 → 214
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:233 → 412
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:415 → 578
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    10. XM_028836501.1 → XP_028692334.1  signal transducer and activator of transcription 3 isoform X11

      UniProtKB/TrEMBL
      G7NIL1, H9ZCT6
      Related
      ENSMMUP00000014032.4, ENSMMUT00000014977.4
      Conserved Domains (4) summary
      cd10374
      Location:563 → 724
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:2 → 120
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:139 → 327
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:330 → 493
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    11. XM_028836495.1 → XP_028692328.1  signal transducer and activator of transcription 3 isoform X5

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Related
      ENSMMUP00000043986.2, ENSMMUT00000076650.2
      Conserved Domains (4) summary
      cd10374
      Location:648 → 809
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:96 → 214
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:233 → 412
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:415 → 578
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    12. XM_028836492.1 → XP_028692325.1  signal transducer and activator of transcription 3 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:657 → 818
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:96 → 214
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:233 → 421
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:424 → 587
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)

    13. XM_028836494.1 → XP_028692327.1  signal transducer and activator of transcription 3 isoform X4

      UniProtKB/TrEMBL
      A0A1D5Q7H0
      Conserved Domains (4) summary
      cd10374
      Location:649 → 810
      SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
      smart00964
      Location:97 → 215
      STAT_int; STAT protein, protein interaction domain
      cd16853
      Location:234 → 413
      STAT3_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 3 (STAT3)
      cd16847
      Location:416 → 579
      STAT3_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 3 (STAT3)
    Nucleotide Protein
    Heading Accession and Version

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