Or6k4 olfactory receptor family 6 subfamily K member 4 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Or6k4provided by MGI
Official Full Name: olfactory receptor family 6 subfamily K member 4provided by MGI
Primary source: MGI:MGI:3030258
See related: Ensembl:ENSMUSG00000051528 AllianceGenome:MGI:3030258
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Olfr424; MOR105-2
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs: human all
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Genomic context

Location:: 1 H3; 1 80.92 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (173964312..173965259)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (174136746..174137693)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables odorant binding	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	ISA Inferred from Sequence Alignment more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sensory perception of smell	ISA Inferred from Sequence Alignment more info	PubMed

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	ISA Inferred from Sequence Alignment more info	PubMed

General protein information

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Preferred Names: olfactory receptor 424

Names: GA_x6K02T2P20D-21025190-21024243; olfactory receptor MOR105-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_146721.2 → NP_666932.2 olfactory receptor 424

Status: VALIDATED

Source sequence(s)

AC113483, BC104096

Consensus CDS

CCDS15538.1

UniProtKB/TrEMBL

E9Q0Q2, Q8VFZ1

Related

ENSMUSP00000054305.4, ENSMUST00000053941.4

Conserved Domains (2) summary

pfam00001
Location:41 → 289

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:35 → 305

7tm_4; Olfactory receptor