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    Ssr4 signal sequence receptor, delta [ Mus musculus (house mouse) ]

    Gene ID: 20832, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ssr4provided by MGI
    Official Full Name
    signal sequence receptor, deltaprovided by MGI
    Primary source
    MGI:MGI:1099464
    See related
    Ensembl:ENSMUSG00000002014 AllianceGenome:MGI:1099464
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Trap; SSR-delta; TRAP-delta
    Summary
    Predicted to be located in endoplasmic reticulum. Predicted to be part of Sec61 translocon complex. Predicted to be active in endomembrane system. Is expressed in several structures, including gut; jaw; musculoskeletal system; nasal capsule; and submandibular gland primordium. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iy. Orthologous to human SSR4 (signal sequence receptor subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 108.4), duodenum adult (RPKM 90.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ssr4 in Genome Data Viewer
    Location:
    X A7.3; X 37.41 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (72830778..72834432)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (73787023..73790828)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene serine/arginine-rich protein specific kinase 3 Neighboring gene STARR-positive B cell enhancer ABC_E11049 Neighboring gene isocitrate dehydrogenase 3 (NAD+), gamma Neighboring gene STARR-seq mESC enhancer starr_47355 Neighboring gene PDZ domain containing 4 Neighboring gene STARR-seq mESC enhancer starr_47357 Neighboring gene predicted gene, 23615 Neighboring gene STARR-seq mESC enhancer starr_47358 Neighboring gene STARR-seq mESC enhancer starr_47359 Neighboring gene L1 cell adhesion molecule

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of Sec61 translocon complex  
    is_active_in endomembrane system  
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum membrane  

    General protein information

    Preferred Names
    translocon-associated protein subunit delta
    Names
    signal sequence receptor subunit delta

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166480.3NP_001159952.1  translocon-associated protein subunit delta isoform 1 precursor

      See identical proteins and their annotated locations for NP_001159952.1

      Status: VALIDATED

      Source sequence(s)
      AL672094
      Consensus CDS
      CCDS53099.1
      UniProtKB/TrEMBL
      Q9D8L3, Q9DC94
      Related
      ENSMUSP00000131386.2, ENSMUST00000166518.8
      Conserved Domains (1) summary
      pfam05404
      Location:22172
      TRAP-delta; Translocon-associated protein, delta subunit precursor (TRAP-delta)
    2. NM_001358212.2NP_001345141.1  translocon-associated protein subunit delta isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AL672094
      Conserved Domains (1) summary
      pfam05404
      Location:22117
      TRAP-delta; Translocon-associated protein, delta subunit precursor (TRAP-delta)
    3. NM_001358213.2NP_001345142.1  translocon-associated protein subunit delta isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL672094
      Conserved Domains (1) summary
      pfam05404
      Location:1109
      TRAP-delta; Translocon-associated protein, delta subunit precursor (TRAP-delta)
    4. NM_001426003.1NP_001412932.1  translocon-associated protein subunit delta isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AL672094
    5. NM_001426004.1NP_001412933.1  translocon-associated protein subunit delta isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL672094
    6. NM_009279.5NP_033305.1  translocon-associated protein subunit delta isoform 2 precursor

      See identical proteins and their annotated locations for NP_033305.1

      Status: VALIDATED

      Source sequence(s)
      AL672094
      Consensus CDS
      CCDS30213.1
      UniProtKB/Swiss-Prot
      Q62186
      UniProtKB/TrEMBL
      Q3TVJ8, Q9D6F7
      Related
      ENSMUSP00000002090.3, ENSMUST00000002090.3
      Conserved Domains (1) summary
      pfam05404
      Location:22171
      TRAP-delta; Translocon-associated protein, delta subunit precursor (TRAP-delta)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      72830778..72834432
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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