Vmn2r111 vomeronasal 2, receptor 111 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Vmn2r111provided by MGI
Official Full Name: vomeronasal 2, receptor 111provided by MGI
Primary source: MGI:MGI:3647034
See related: Ensembl:ENSMUSG00000095093 AllianceGenome:MGI:3647034
Gene type: protein coding
RefSeq status: INFERRED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: V2rp2; EG210876
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 17 A3.3; 17 11.4 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (22766922..22792254, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (22547941..22573273, complement)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

identification of a male-specific 7-kDa peptide secreted from the extraorbital lacrimal gland; ESP1 is secreted from the eyes and is transferred to the female vomeronasal organ, where it stimulates pheromone receptor-expressing vomeronasal sensory neurons
Title: Sex-specific peptides from exocrine glands stimulate mouse vomeronasal sensory neurons.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: vomeronasal receptor Vmn2r111

Names: vomeronasal 2 receptor p2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001104573.1 → NP_001098043.1 vomeronasal receptor Vmn2r111 precursor

See identical proteins and their annotated locations for NP_001098043.1

Status: INFERRED

Source sequence(s)

AC122270

Consensus CDS

CCDS50002.1

UniProtKB/TrEMBL

A0A3Q4EH53, D7URW2, K7N674

Related

ENSMUSP00000090148.6, ENSMUST00000092491.7

Conserved Domains (4) summary

cd06365
Location:41 → 504

PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

pfam00003
Location:599 → 832

7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR

pfam01094
Location:75 → 471

ANF_receptor; Receptor family ligand binding region

pfam07562
Location:513 → 564

NCD3G; Nine Cysteines Domain of family 3 GPCR