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    Btbd7 BTB domain containing 7 [ Mus musculus (house mouse) ]

    Gene ID: 238386, updated on 27-Nov-2024

    Summary

    Official Symbol
    Btbd7provided by MGI
    Official Full Name
    BTB domain containing 7provided by MGI
    Primary source
    MGI:MGI:1917858
    See related
    Ensembl:ENSMUSG00000041702 AllianceGenome:MGI:1917858
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FUP1; mKIAA1525; 8030448M07; 5730507E09Rik; E130118E17Rik
    Summary
    Acts upstream of or within regulation of branching involved in salivary gland morphogenesis. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and submandibular gland primordium. Orthologous to human BTBD7 (BTB domain containing 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 6.7), bladder adult (RPKM 6.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Btbd7 in Genome Data Viewer
    Location:
    12 E; 12 52.25 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (102747056..102844733, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (102780797..102878471, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_33118 Neighboring gene predicted gene 20604 Neighboring gene STARR-seq mESC enhancer starr_33119 Neighboring gene GON7 subunit of KEOPS complex Neighboring gene ubiquitin protein ligase E3 component n-recognin 7 (putative) Neighboring gene cytochrome c oxidase subunit 7C, mitochondrial pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8503 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene cytochrome c oxidase subunit 8C Neighboring gene unc-79 homolog Neighboring gene STARR-seq mESC enhancer starr_33121

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    General gene information

    Markers

    Clone Names

    • MGC49574

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    BTB/POZ domain-containing protein 7
    Names
    BTB (POZ) domain containing 7
    function-unkown protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001377026.1NP_001363955.1  BTB/POZ domain-containing protein 7

      Status: VALIDATED

      Source sequence(s)
      AC122367, AC132315
      UniProtKB/Swiss-Prot
      Q80TC3, Q8BZY9, Q8CFE5
      Related
      ENSMUSP00000046951.7, ENSMUST00000045652.8
      Conserved Domains (3) summary
      cd18283
      Location:140231
      BTB1_POZ_BTBD7; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
      cd18284
      Location:245392
      BTB2_POZ_BTBD7; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
      cd18489
      Location:397494
      BACK_BTBD7; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
    2. NM_172806.3NP_766394.2  BTB/POZ domain-containing protein 7

      See identical proteins and their annotated locations for NP_766394.2

      Status: VALIDATED

      Source sequence(s)
      AC122367, AC132315
      Consensus CDS
      CCDS26125.1
      UniProtKB/Swiss-Prot
      Q80TC3, Q8BZY9, Q8CFE5
      Related
      ENSMUSP00000152426.2, ENSMUST00000223554.2
      Conserved Domains (3) summary
      cd18283
      Location:140231
      BTB1_POZ_BTBD7; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
      cd18284
      Location:245392
      BTB2_POZ_BTBD7; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
      cd18489
      Location:397494
      BACK_BTBD7; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 7 (BTBD7)

    RNA

    1. NR_165048.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC122367, AC132315

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      102747056..102844733 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157405.1XP_036013298.1  BTB/POZ domain-containing protein 7 isoform X1

    2. XM_036157406.1XP_036013299.1  BTB/POZ domain-containing protein 7 isoform X2

      Conserved Domains (2) summary
      cd18283
      Location:140231
      BTB1_POZ_BTBD7; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
      cd18284
      Location:245388
      BTB2_POZ_BTBD7; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)

    RNA

    1. XR_004937501.1 RNA Sequence