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    Unc79 unc-79 homolog [ Mus musculus (house mouse) ]

    Gene ID: 217843, updated on 9-Dec-2024

    Summary

    Official Symbol
    Unc79provided by MGI
    Official Full Name
    unc-79 homologprovided by MGI
    Primary source
    MGI:MGI:2684729
    See related
    Ensembl:ENSMUSG00000021198 AllianceGenome:MGI:2684729
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mlca3; 9030205A07Rik
    Summary
    Acts upstream of or within behavioral response to ethanol and suckling behavior. Predicted to be located in plasma membrane. Orthologous to human UNC79 (unc-79 homolog, NALCN channel complex subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 7.5), whole brain E14.5 (RPKM 7.5) and 7 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Unc79 in Genome Data Viewer
    Location:
    12 E; 12 52.68 cM
    Exon count:
    53
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (102913642..103150487)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (102947383..103184228)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene BTB domain containing 7 Neighboring gene STARR-positive B cell enhancer ABC_E8503 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene cytochrome c oxidase subunit 8C Neighboring gene STARR-seq mESC enhancer starr_33121 Neighboring gene proline rich membrane anchor 1 Neighboring gene STARR-positive B cell enhancer ABC_E7173 Neighboring gene family with sequence similarity 181, member A Neighboring gene predicted gene 29508

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1409

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    protein unc-79 homolog
    Names
    modifier of locomotor activity 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081017.2NP_001074486.2  protein unc-79 homolog

      See identical proteins and their annotated locations for NP_001074486.2

      Status: VALIDATED

      Source sequence(s)
      AC122367, AC151982, AC165074
      Consensus CDS
      CCDS49149.2
      UniProtKB/Swiss-Prot
      Q0KK54, Q0KK59, Q6L9U9, Q8CCC5
      UniProtKB/TrEMBL
      E5CYJ9
      Related
      ENSMUSP00000098659.6, ENSMUST00000101099.12
      Conserved Domains (1) summary
      pfam14776
      Location:113645
      UNC-79; Cation-channel complex subunit UNC-79

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      102913642..103150487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157347.1XP_036013240.1  protein unc-79 homolog isoform X5

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:114645
      UNC-79; Cation-channel complex subunit UNC-79
    2. XM_036157360.1XP_036013253.1  protein unc-79 homolog isoform X18

      UniProtKB/TrEMBL
      E5CYJ9
      Related
      ENSMUSP00000136332.2, ENSMUST00000179002.8
      Conserved Domains (1) summary
      pfam14776
      Location:61592
      UNC-79; Cation-channel complex subunit UNC-79
    3. XM_036157361.1XP_036013254.1  protein unc-79 homolog isoform X19

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:47578
      UNC-79; Cation-channel complex subunit UNC-79
    4. XM_036157364.1XP_036013257.1  protein unc-79 homolog isoform X22

      UniProtKB/TrEMBL
      J3QNP0
      Related
      ENSMUSP00000136888.2, ENSMUST00000178076.8
      Conserved Domains (1) summary
      pfam14776
      Location:3468
      UNC-79; Cation-channel complex subunit UNC-79
    5. XM_036157365.1XP_036013258.1  protein unc-79 homolog isoform X23

      UniProtKB/TrEMBL
      J3QNP0
      Conserved Domains (1) summary
      pfam14776
      Location:6277
      UNC-79; Cation-channel complex subunit UNC-79
    6. XM_036157344.1XP_036013237.1  protein unc-79 homolog isoform X1

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    7. XM_036157350.1XP_036013243.1  protein unc-79 homolog isoform X8

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    8. XM_036157353.1XP_036013246.1  protein unc-79 homolog isoform X11

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    9. XM_036157352.1XP_036013245.1  protein unc-79 homolog isoform X10

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    10. XM_036157348.1XP_036013241.1  protein unc-79 homolog isoform X6

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    11. XM_036157358.1XP_036013251.1  protein unc-79 homolog isoform X16

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    12. XM_036157355.1XP_036013248.1  protein unc-79 homolog isoform X13

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    13. XM_036157354.1XP_036013247.1  protein unc-79 homolog isoform X12

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:88619
      UNC-79; Cation-channel complex subunit UNC-79
    14. XM_036157349.1XP_036013242.1  protein unc-79 homolog isoform X7

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    15. XM_006515743.4XP_006515806.1  protein unc-79 homolog isoform X2

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (3) summary
      pfam07964
      Location:16942015
      Red1; Rec10 / Red1
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
      cl02544
      Location:812873
      VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily
    16. XM_036157351.1XP_036013244.1  protein unc-79 homolog isoform X9

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    17. XM_036157362.1XP_036013255.1  protein unc-79 homolog isoform X20

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    18. XM_036157345.1XP_036013238.1  protein unc-79 homolog isoform X3

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    19. XM_036157346.1XP_036013239.1  protein unc-79 homolog isoform X4

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    20. XM_036157357.1XP_036013250.1  protein unc-79 homolog isoform X15

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    21. XM_036157359.1XP_036013252.1  protein unc-79 homolog isoform X17

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    22. XM_036157363.1XP_036013256.1  protein unc-79 homolog isoform X21

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:141672
      UNC-79; Cation-channel complex subunit UNC-79
    23. XM_036157356.1XP_036013249.1  protein unc-79 homolog isoform X14

      UniProtKB/TrEMBL
      E5CYJ9
      Conserved Domains (1) summary
      pfam14776
      Location:88619
      UNC-79; Cation-channel complex subunit UNC-79

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_177621.2: Suppressed sequence

      Description
      NM_177621.2: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.