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    Otos otospiralin [ Mus musculus (house mouse) ]

    Gene ID: 260301, updated on 9-Dec-2024

    Summary

    Official Symbol
    Otosprovided by MGI
    Official Full Name
    otospiralinprovided by MGI
    Primary source
    MGI:MGI:2672814
    See related
    Ensembl:ENSMUSG00000044055 AllianceGenome:MGI:2672814
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    OTOSP
    Summary
    Acts upstream of or within sensory perception of sound. Predicted to be located in extracellular region. Is expressed in inner ear mesenchyme and spiral ligament. Orthologous to human OTOS (otospiralin). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Otos in Genome Data Viewer
    Location:
    1 D; 1 46.55 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (92571940..92576630, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (92644218..92648899, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_01719 Neighboring gene STARR-seq mESC enhancer starr_01720 Neighboring gene olfactory receptor family 9 subfamily S member 13 Neighboring gene COP9 signalosome subunit 9 Neighboring gene STARR-seq mESC enhancer starr_01721 Neighboring gene predicted gene 29483 Neighboring gene predicted gene, 36102

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General protein information

    Preferred Names
    otospiralin
    Names
    organ of Corti 10 kDa protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153114.2NP_694754.1  otospiralin precursor

      See identical proteins and their annotated locations for NP_694754.1

      Status: PROVISIONAL

      Source sequence(s)
      BC100323
      Consensus CDS
      CCDS35668.1
      UniProtKB/Swiss-Prot
      Q8R448
      UniProtKB/TrEMBL
      Q497Y7
      Related
      ENSMUSP00000061683.4, ENSMUST00000053144.4
      Conserved Domains (1) summary
      pfam15182
      Location:2189
      OTOS; Otospiralin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      92571940..92576630 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320818.3XP_017176307.1  otospiralin isoform X1

      UniProtKB/Swiss-Prot
      Q8R448
      UniProtKB/TrEMBL
      Q497Y7
      Conserved Domains (1) summary
      pfam15182
      Location:2189
      OTOS; Otospiralin
    2. XM_017320815.2XP_017176304.1  otospiralin isoform X1

      UniProtKB/Swiss-Prot
      Q8R448
      UniProtKB/TrEMBL
      Q497Y7
      Conserved Domains (1) summary
      pfam15182
      Location:2189
      OTOS; Otospiralin