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    Vmn2r14 vomeronasal 2, receptor 14 [ Mus musculus (house mouse) ]

    Gene ID: 231591, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Vmn2r14provided by MGI
    Official Full Name
    vomeronasal 2, receptor 14provided by MGI
    Primary source
    MGI:MGI:3649151
    See related
    Ensembl:ENSMUSG00000091059 AllianceGenome:MGI:3649151
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG231591
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn2r14 in Genome Data Viewer
    Location:
    5 F; 5 53.24 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (109362822..109372488, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (109214956..109224622, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13916 Neighboring gene vomeronasal 2, receptor 12 Neighboring gene vomeronasal 2, receptor 13 Neighboring gene RAD21 homolog pseudogene Neighboring gene vomeronasal 2, receptor 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor 14
    Names
    vomeronasal receptor Vmn2r14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104625.1 → NP_001098095.1  vomeronasal 2, receptor 14 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC123748
      Consensus CDS
      CCDS51600.1
      UniProtKB/TrEMBL
      E9Q759
      Related
      ENSMUSP00000128015.2, ENSMUST00000170341.3
      Conserved Domains (3) summary
      cd06365
      Location:40 → 499
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:595 → 829
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam07562
      Location:508 → 560
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. NM_001384975.1 → NP_001371904.1  vomeronasal 2, receptor 14 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC123748
      Conserved Domains (3) summary
      cd15283
      Location:580 → 831
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:45 → 496
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:507 → 560
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      109362822..109372488 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320860.1 → XP_017176349.1  vomeronasal 2, receptor 14 isoform X2

      Conserved Domains (3) summary
      cd15283
      Location:581 → 832
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:507 → 561
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd06365
      Location:45 → 496
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    2. XM_036165084.1 → XP_036020977.1  vomeronasal 2, receptor 14 isoform X4

      Conserved Domains (3) summary
      cd15283
      Location:505 → 756
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:432 → 485
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:45 → 441
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_030254415.1 → XP_030110275.1  vomeronasal 2, receptor 14 isoform X1

      Conserved Domains (3) summary
      cd15283
      Location:582 → 833
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:509 → 562
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd06365
      Location:45 → 496
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    4. XM_030254417.1 → XP_030110277.1  vomeronasal 2, receptor 14 isoform X3

      Conserved Domains (2) summary
      cd15283
      Location:540 → 791
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:45 → 496
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    5. XM_017320862.1 → XP_017176351.1  vomeronasal 2, receptor 14 isoform X6

      Conserved Domains (1) summary
      cl10011
      Location:45 → 431
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    6. XM_017320861.1 → XP_017176350.1  vomeronasal 2, receptor 14 isoform X5

      Conserved Domains (1) summary
      cl10011
      Location:45 → 430
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version

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