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    Ociad2 OCIA domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 433904, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ociad2provided by MGI
    Official Full Name
    OCIA domain containing 2provided by MGI
    Primary source
    MGI:MGI:1916377
    See related
    Ensembl:ENSMUSG00000029153 AllianceGenome:MGI:1916377
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810027I20Rik
    Summary
    Acts upstream of or within response to bacterium. Located in mitochondrial inner membrane. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human OCIAD2 (OCIA domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in frontal lobe adult (RPKM 17.9), bladder adult (RPKM 14.8) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ociad2 in Genome Data Viewer
    Location:
    5 C3.3; 5 38.54 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (73479541..73496290, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (73322198..73338947, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13383 Neighboring gene predicted gene, 40316 Neighboring gene STARR-seq mESC enhancer starr_13384 Neighboring gene OCIA domain containing 1 Neighboring gene STARR-seq mESC enhancer starr_13385 Neighboring gene predicted gene, 34496 Neighboring gene STARR-seq mESC enhancer starr_13386 Neighboring gene predicted gene, 34583

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Scavuzzo MA, et al. Nat Commun, 2018 Aug 22. PMID 30135482, Free PMC Article
    2. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article
    3. Proteomic analysis of the mouse liver mitochondrial inner membrane. Da Cruz S, et al. J Biol Chem, 2003 Oct 17. PMID 12865426
    4. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
    5. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Clone Names

    • MGC51598

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    OCIA domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310636.1 → NP_001297565.1  OCIA domain-containing protein 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a shorter, distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC108828
      Consensus CDS
      CCDS80301.1
      UniProtKB/TrEMBL
      A0A0J9YU56, A0A0J9YUI7
      Related
      ENSMUSP00000144012.2, ENSMUST00000201908.4
      Conserved Domains (1) summary
      pfam07051
      Location:12 → 88
      OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)

    2. NM_026950.4 → NP_081226.1  OCIA domain-containing protein 2 isoform 1

      See identical proteins and their annotated locations for NP_081226.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC108828, AK007617, CJ146723
      Consensus CDS
      CCDS19340.1
      UniProtKB/Swiss-Prot
      Q9D8W7
      Related
      ENSMUSP00000084445.6, ENSMUST00000087195.9
      Conserved Domains (1) summary
      pfam07051
      Location:33 → 117
      OCIA; Ovarian carcinoma immunoreactive antigen (OCIA)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      73479541..73496290 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D8W7.1 GenPept UniProtKB/Swiss-Prot:Q9D8W7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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