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    Slc35e2 solute carrier family 35, member E2 [ Mus musculus (house mouse) ]

    Gene ID: 320541, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc35e2provided by MGI
    Official Full Name
    solute carrier family 35, member E2provided by MGI
    Primary source
    MGI:MGI:2444240
    See related
    Ensembl:ENSMUSG00000042202 AllianceGenome:MGI:2444240
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Slc35e2a; A530082C11Rik
    Summary
    Predicted to enable antiporter activity. Acts upstream of or within blastocyst hatching. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including cardiovascular system; central nervous system; endocrine gland; genitourinary system; and trachea. Orthologous to several human genes including SLC35E2B (solute carrier family 35 member E2B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 6.1), adrenal adult (RPKM 5.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Slc35e2 in Genome Data Viewer
    Location:
    4 E2; 4 86.62 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (155685873..155707797)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (155601416..155623340)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene guanine nucleotide binding protein (G protein), beta 1 Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 pseudogene Neighboring gene STARR-seq mESC enhancer starr_12266 Neighboring gene STARR-positive B cell enhancer ABC_E340 Neighboring gene STARR-positive B cell enhancer ABC_E10296 Neighboring gene NAD kinase Neighboring gene STARR-positive B cell enhancer ABC_E3559 Neighboring gene predicted gene 16023 Neighboring gene cyclin dependent kinase 11B Neighboring gene matrix metallopeptidase 23 Neighboring gene mindbomb E3 ubiquitin protein ligase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst hatching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    solute carrier family 35 member E2A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177186.4NP_796160.1  solute carrier family 35 member E2A

      See identical proteins and their annotated locations for NP_796160.1

      Status: VALIDATED

      Source sequence(s)
      AK142259, BC058728
      Consensus CDS
      CCDS38995.1
      UniProtKB/Swiss-Prot
      Q8C811
      Related
      ENSMUSP00000101233.3, ENSMUST00000105608.9
      Conserved Domains (1) summary
      cl26744
      Location:73368
      TPT; Triose-phosphate Transporter family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      155685873..155707797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538952.5XP_006539015.1  solute carrier family 35 member E2A isoform X1

      See identical proteins and their annotated locations for XP_006539015.1

      UniProtKB/Swiss-Prot
      Q8C811
      Related
      ENSMUSP00000113189.2, ENSMUST00000118607.2
      Conserved Domains (1) summary
      cl26744
      Location:73368
      TPT; Triose-phosphate Transporter family
    2. XM_006538953.4XP_006539016.1  solute carrier family 35 member E2A isoform X1

      See identical proteins and their annotated locations for XP_006539016.1

      UniProtKB/Swiss-Prot
      Q8C811
      Conserved Domains (1) summary
      cl26744
      Location:73368
      TPT; Triose-phosphate Transporter family