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    Rv2004c hypothetical protein [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 888817, updated on 6-Jun-2024

    Summary

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    Gene symbol
    Rv2004c
    Gene description
    hypothetical protein
    Locus tag
    Rv2004c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (2249478..2250974, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene 3-alpha(or 20-beta)-hydroxysteroid dehydrogenase Neighboring gene hypothetical protein Neighboring gene universal stress protein Neighboring gene trehalose-6-phosphate phosphatase OtsB

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mycobacterium tuberculosis DosR regulon gene Rv2004c contributes to streptomycin resistance and intracellular survival. Doddam SN, et al. Int J Med Microbiol, 2019 Dec. PMID 31521502
    2. Identifying putative Mycobacterium tuberculosis Rv2004c protein sequences that bind specifically to U937 macrophages and A549 epithelial cells. Forero M, et al. Protein Sci, 2005 Nov. PMID 16199660, Free PMC Article
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rv2004c possibly mediates streptomycin resistance through the aminoglycoside phosphotransferase activity.
      Title: Mycobacterium tuberculosis DosR regulon gene Rv2004c contributes to streptomycin resistance and intracellular survival.
    2. Surface localization and cell-binding capacity of the Rv2004c protein to U937 macrophages and A549 epithelial cells.
      Title: Identifying putative Mycobacterium tuberculosis Rv2004c protein sequences that bind specifically to U937 macrophages and A549 epithelial cells.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    hypothetical protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      2249478..2250974 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_216520.1 hypothetical protein Rv2004c [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_216520.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A654TM39
      Conserved Domains (2) summary
      COG0645
      Location:323 → 495
      COG0645; Predicted kinase [General function prediction only]
      COG2187
      Location:1 → 322
      COG2187; Aminoglycoside phosphotransferase family enzyme [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WLN3.1

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