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    Rv0147 aldehyde dehydrogenase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886847, updated on 6-Jun-2024

    Summary

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    Gene symbol
    Rv0147
    Gene description
    aldehyde dehydrogenase
    Locus tag
    Rv0147
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (173238..174758)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine-dependent methyltransferase Neighboring gene S-adenosylmethionine-dependent methyltransferase Neighboring gene short-chain type dehydrogenase/reductase Neighboring gene quinone oxidoreductase Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cellular immune response in MDR-TB patients to different protein expression of MDR and susceptible Mycobacterium tuberculosis: Rv0147, a novel MDR-TB biomarker. Hadizadeh Tasbiti A, et al. Immunol Res, 2018 Feb. PMID 29178041
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. these results suggest that the purified protein, Rv0147, may stimulate Th1 type protective cytokine response in multidrug resistant tuberculosis patients but not in normal subjects
      Title: Cellular immune response in MDR-TB patients to different protein expression of MDR and susceptible Mycobacterium tuberculosis: Rv0147, a novel MDR-TB biomarker.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    aldehyde dehydrogenase
    NP_214661.1
    • Belongs to the aldehyde dehydrogenases family.

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      173238..174758
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_214661.1 aldehyde dehydrogenase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_214661.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0U0QLZ5, A0A655HM22
      Conserved Domains (1) summary
      cd07087
      Location:51 → 479
      ALDH_F3-13-14_CALDH-like; ALDH subfamily: Coniferyl aldehyde dehydrogenase, ALDH families 3, 13, and 14, and other related proteins
    Nucleotide Protein
    Heading Accession and Version

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