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    aroB 3-dehydroquinate synthase [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 888392, updated on 6-Oct-2023

    Summary

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    Gene symbol
    aroB
    Gene description
    3-dehydroquinate synthase
    Locus tag
    Rv2538c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (2861588..2862676, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene cytoplasmic peptidase PepQ Neighboring gene transmembrane protein Neighboring gene 3-dehydroquinate dehydratase Neighboring gene shikimate kinase Neighboring gene chorismate synthase Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In silico docking and molecular dynamics simulation of 3-dehydroquinate synthase (DHQS) from Mycobacterium tuberculosis. Isa MA, et al. J Mol Model, 2018 May 11. PMID 29752576
    2. Functional characterization by genetic complementation of aroB-encoded dehydroquinate synthase from Mycobacterium tuberculosis H37Rv and its heterologous expression and purification. de Mendonça JD, et al. J Bacteriol, 2007 Sep. PMID 17586643, Free PMC Article
    3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. In silico docking and molecular dynamics simulation of 3-dehydroquinate synthase (DHQS) from Mycobacterium tuberculosis.
      Title: In silico docking and molecular dynamics simulation of 3-dehydroquinate synthase (DHQS) from Mycobacterium tuberculosis.
    2. study presents the cloning, purification, and genetic complementation of the aroB gene
      Title: Functional characterization by genetic complementation of aroB-encoded dehydroquinate synthase from Mycobacterium tuberculosis H37Rv and its heterologous expression and purification.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    3-dehydroquinate synthase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      2861588..2862676 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_217054.1 3-dehydroquinate synthase [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_217054.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A654ZWS4
      Conserved Domains (1) summary
      PRK00002
      Location:8 → 361
      aroB; 3-dehydroquinate synthase; Reviewed
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P9WPX9.1

    Gene LinkOut

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