U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    LPAR1 lysophosphatidic acid receptor 1 [ Homo sapiens (human) ]

    Gene ID: 1902, updated on 3-Dec-2024

    Summary

    Official Symbol
    LPAR1provided by HGNC
    Official Full Name
    lysophosphatidic acid receptor 1provided by HGNC
    Primary source
    HGNC:HGNC:3166
    See related
    Ensembl:ENSG00000198121 MIM:602282; AllianceGenome:HGNC:3166
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    EDG2; LPA1; VZG1; edg-2; vzg-1; Gpcr26; Mrec1.3; rec.1.3
    Summary
    The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene. [provided by RefSeq, Oct 2020]
    Expression
    Ubiquitous expression in brain (RPKM 14.7), placenta (RPKM 8.1) and 22 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See LPAR1 in Genome Data Viewer
    Location:
    9q31.3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (110873263..111038998, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (123044905..123210649, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (113635543..113801278, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr9:113490321-113490840 Neighboring gene muscle associated receptor tyrosine kinase Neighboring gene Sharpr-MPRA regulatory region 6532 Neighboring gene uncharacterized LOC107987115 Neighboring gene ribosomal protein S21 pseudogene 5 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:113544666-113545865 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:113553096-113553668 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28787 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28788 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105418 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105435 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105449 Neighboring gene RNA, U6 small nuclear 432, pseudogene Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105469 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28790 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28789 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28791 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20175 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:113715081-113715580 Neighboring gene uncharacterized LOC124902248 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20176 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28792 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:113861264-113862248 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105528 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105563 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105573 Neighboring gene RNY4 pseudogene 18 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105610 Neighboring gene VISTA enhancer hs1447 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_105661 Neighboring gene microRNA 7702

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
    EBI GWAS Catalog
    Hundreds of variants clustered in genomic loci and biological pathways affect human height.
    EBI GWAS Catalog
    Multiple loci are associated with white blood cell phenotypes.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables G-protein alpha-subunit binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables PDZ domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables lysophosphatidic acid binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables lysophosphatidic acid receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lysophosphatidic acid receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables lysophosphatidic acid receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in bleb assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to 1-oleoyl-sn-glycerol 3-phosphate IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to oxygen levels IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cerebellum development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in corpus callosum development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in myelination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of cAMP-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of cilium assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in neurogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in oligodendrocyte development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in optic nerve development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of Rho protein signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of canonical NF-kappaB signal transduction IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of dendritic spine development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of smooth muscle cell chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of stress fiber assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of cell shape ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of postsynaptic neurotransmitter receptor internalization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of synaptic vesicle cycle IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in GABA-ergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in dendritic shaft IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with endocytic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lysophosphatidic acid receptor 1
    Names
    LPA receptor 1
    LPA-1
    endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2
    lysophosphatidic acid receptor Edg-2
    ventricular zone gene 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001351397.2NP_001338326.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DA479098
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    2. NM_001351398.2NP_001338327.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DA088664, DA479098
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    3. NM_001351399.2NP_001338328.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DA479098
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    4. NM_001351400.2NP_001338329.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DA088664, DC327578
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    5. NM_001351401.2NP_001338330.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DC327578, DC340753, DC418941
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    6. NM_001351402.2NP_001338331.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DC418941
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    7. NM_001351403.2NP_001338332.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DC327578
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    8. NM_001351404.2NP_001338333.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DC327578, DC340753
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    9. NM_001351405.2NP_001338334.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DC327578, DC422078
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    10. NM_001351406.2NP_001338335.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DB477196, DC325182
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    11. NM_001351407.2NP_001338336.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DA088664, DB477196, DC325182
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    12. NM_001351408.2NP_001338337.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DB477196, DC418941
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    13. NM_001351409.2NP_001338338.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DB477196, DC340753, DC418941
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    14. NM_001351410.2NP_001338339.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, AK290287, BC036034, DB477196, DC418941, DC422078
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    15. NM_001351411.2NP_001338340.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DB477196, DC325182, DC340753
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Related
      ENSP00000506912.1, ENST00000683809.1
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    16. NM_001351412.2NP_001338341.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, CN360217, DB477196, DC422078
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    17. NM_001351413.2NP_001338342.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, CN360217, DB477196, DC422078
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    18. NM_001351414.2NP_001338343.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DB477196, DC340753, DC422078
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    19. NM_001351415.2NP_001338344.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AC007157, AI674417, AK022808, AK290287, BC036034, DA088664, DC325182, DC418941
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    20. NM_001351416.2NP_001338345.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AC007157, AI674417, AK022808, AK290287, BC036034, DC418941
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    21. NM_001351417.2NP_001338346.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AC007157, AI674417, AK022808, BC036034, DC340753
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    22. NM_001351418.2NP_001338347.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AC007157, AI674417, AK022808, BC036034, CN360217, DB477196, DC340753, DC422078
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    23. NM_001351419.2NP_001338348.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AC007157, AI674417, AK022808, BC036034, DC340753
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    24. NM_001351420.2NP_001338349.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (26) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AI674417, AK022808, BC036034, DA327368
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    25. NM_001387470.1NP_001374399.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    26. NM_001387471.1NP_001374400.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    27. NM_001387472.1NP_001374401.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    28. NM_001387473.1NP_001374402.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    29. NM_001387474.1NP_001374403.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    30. NM_001387475.1NP_001374404.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    31. NM_001387476.1NP_001374405.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    32. NM_001387477.1NP_001374406.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    33. NM_001387478.1NP_001374407.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    34. NM_001387479.1NP_001374408.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    35. NM_001387480.1NP_001374409.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    36. NM_001387481.1NP_001374410.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    37. NM_001387482.1NP_001374411.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    38. NM_001387483.1NP_001374412.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    39. NM_001387484.1NP_001374413.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    40. NM_001387485.1NP_001374414.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    41. NM_001387486.1NP_001374415.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    42. NM_001387487.1NP_001374416.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    43. NM_001387488.1NP_001374417.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    44. NM_001387489.1NP_001374418.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    45. NM_001387490.1NP_001374419.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    46. NM_001387491.1NP_001374420.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    47. NM_001387492.1NP_001374421.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    48. NM_001387493.1NP_001374422.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    49. NM_001387494.1NP_001374423.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    50. NM_001387495.1NP_001374424.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    51. NM_001387496.1NP_001374425.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    52. NM_001387497.1NP_001374426.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    53. NM_001387498.1NP_001374427.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    54. NM_001387501.1NP_001374430.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    55. NM_001387502.1NP_001374431.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    56. NM_001387503.1NP_001374432.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    57. NM_001387504.1NP_001374433.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    58. NM_001387505.1NP_001374434.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    59. NM_001387506.1NP_001374435.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    60. NM_001387507.1NP_001374436.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    61. NM_001387508.1NP_001374437.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    62. NM_001387509.1NP_001374438.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    63. NM_001387510.1NP_001374439.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    64. NM_001387511.1NP_001374440.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    65. NM_001387512.1NP_001374441.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    66. NM_001387513.1NP_001374442.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    67. NM_001387514.1NP_001374443.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    68. NM_001387515.1NP_001374444.1  lysophosphatidic acid receptor 1 isoform a

      Status: REVIEWED

      Source sequence(s)
      AL157881, AL442064
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Related
      ENSP00000363552.1, ENST00000374430.6
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    69. NM_001387516.1NP_001374445.1  lysophosphatidic acid receptor 1 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      UniProtKB/TrEMBL
      B4DQ18, Q6GPG7
      Conserved Domains (1) summary
      cd15344
      Location:32304
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    70. NM_001387517.1NP_001374446.1  lysophosphatidic acid receptor 1 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL157881, AL442064
      UniProtKB/TrEMBL
      B4DQ18, Q6GPG7
      Conserved Domains (1) summary
      cd15344
      Location:32304
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    71. NM_001387518.1NP_001374447.1  lysophosphatidic acid receptor 1 isoform b

      Status: REVIEWED

      Source sequence(s)
      AL157881, AL442064
      UniProtKB/TrEMBL
      B4DQ18, Q6GPG7
      Conserved Domains (1) summary
      cd15344
      Location:32304
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    72. NM_001387519.1NP_001374448.1  lysophosphatidic acid receptor 1 isoform c

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL442064
      Conserved Domains (2) summary
      cd14964
      Location:5177
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:50267
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    73. NM_001387520.1NP_001374449.1  lysophosphatidic acid receptor 1 isoform c

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL442064
      Conserved Domains (2) summary
      cd14964
      Location:5177
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:50267
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    74. NM_001387521.1NP_001374450.1  lysophosphatidic acid receptor 1 isoform c

      Status: REVIEWED

      Source sequence(s)
      AC007157, AL442064
      Conserved Domains (2) summary
      cd14964
      Location:5177
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:50267
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    75. NM_001401.5NP_001392.2  lysophosphatidic acid receptor 1 isoform a

      See identical proteins and their annotated locations for NP_001392.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AC007157, AI674417, AK022808, BC036034
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Related
      ENSP00000351755.4, ENST00000358883.8
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors
    76. NM_057159.4NP_476500.1  lysophosphatidic acid receptor 1 isoform a

      See identical proteins and their annotated locations for NP_476500.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1-70 all encode the same isoform (a).
      Source sequence(s)
      AC007157, AI674417, AK022808, BC030615, BC036034
      Consensus CDS
      CCDS6777.1
      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0
      Related
      ENSP00000363553.3, ENST00000374431.7
      Conserved Domains (1) summary
      cd15344
      Location:50322
      7tmA_LPAR1_Edg2; lysophosphatidic acid receptor subtype 1 (LPAR1 or LPA1), also called endothelial differentiation gene 2 (Edg2), member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      110873263..111038998 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047422903.1XP_047278859.1  lysophosphatidic acid receptor 1 isoform X1

      UniProtKB/Swiss-Prot
      B4DK36, O00656, O00722, P78351, Q92633
      UniProtKB/TrEMBL
      B4DQ18, Q5VZX0

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      123044905..123210649 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)