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    PA3047 D-alanyl-D-alanine carboxypeptidase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 882878, updated on 11-Sep-2024

    Summary

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    Gene symbol
    PA3047
    Gene description
    D-alanyl-D-alanine carboxypeptidase
    Locus tag
    PA3047
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3410264..3411694)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene two-component response regulator Neighboring gene hypothetical protein Neighboring gene ribosomal RNA large subunit methyltransferase K/L Neighboring gene ribosome modulation factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Catalytic spectrum of the penicillin-binding protein 4 of Pseudomonas aeruginosa, a nexus for the induction of β-lactam antibiotic resistance. Lee M, et al. J Am Chem Soc, 2015 Jan 14. PMID 25495032, Free PMC Article
    2. A potential space-making role in cell wall biogenesis for SltB1and DacB revealed by a beta-lactamase induction phenotype in Pseudomonas aeruginosa. Gyger J, et al. mBio, 2024 Jul 17. PMID 38920394, Free PMC Article
    3. The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis. Sauvage E, et al. FEMS Microbiol Rev, 2008 Mar. PMID 18266856
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A potential space-making role in cell wall biogenesis for SltB1and DacB revealed by a beta-lactamase induction phenotype in Pseudomonas aeruginosa.
      Title: A potential space-making role in cell wall biogenesis for SltB1and DacB revealed by a beta-lactamase induction phenotype in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables serine-type carboxypeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within peptidoglycan biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in periplasmic space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    D-alanyl-D-alanine carboxypeptidase
    NP_251737.1
    • 'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3410264..3411694
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251737.1 D-alanyl-D-alanine carboxypeptidase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251737.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3M5DW99
      Conserved Domains (1) summary
      COG2027
      Location:2 → 476
      DacB; D-alanyl-D-alanine carboxypeptidase [Cell wall/membrane/envelope biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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