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    ldh leucine dehydrogenase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879877, updated on 24-Aug-2024

    Summary

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    Gene symbol
    ldh
    Gene description
    leucine dehydrogenase
    Locus tag
    PA3418
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3824748..3825773, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene branched-chain alpha-keto acid dehydrogenase subunit E2 Neighboring gene pyruvate dehydrogenase E1 component subunit beta Neighboring gene pyruvate dehydrogenase E1 component subunit alpha Neighboring gene hypothetical protein Neighboring gene transcriptional regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Leucine dehydrogenase from Bacillus stearothermophilus: identification of active-site lysine by modification with pyridoxal phosphate. Matsuyama T, et al. J Biochem, 1992 Aug. PMID 1400267
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables L-leucine dehydrogenase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine dehydrogenase
    NP_252108.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3824748..3825773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252108.1 leucine dehydrogenase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252108.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HYI7
      Conserved Domains (1) summary
      COG0334
      Location:1 → 338
      GdhA; Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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