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    Ttc13 tetratricopeptide repeat domain 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292095, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ttc13provided by RGD
    Official Full Name
    tetratricopeptide repeat domain 13provided by RGD
    Primary source
    RGD:1310186
    See related
    EnsemblRapid:ENSRNOG00000018884 AllianceGenome:RGD:1310186
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human TTC13 (tetratricopeptide repeat domain 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 76.5), Spleen (RPKM 57.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ttc13 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (69534989..69589590, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (52637599..52692196, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (57429980..57484583, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 1 open reading frame 198 Neighboring gene uncharacterized LOC120098646 Neighboring gene ARV1 homolog, fatty acid homeostasis modulator Neighboring gene family with sequence similarity 89, member A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    tetratricopeptide repeat protein 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136162.2 → NP_001129634.1  tetratricopeptide repeat protein 13 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      F1LR77
      Conserved Domains (4) summary
      sd00006
      Location:181 → 209
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:249 → 282
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:217 → 279
      TPR_11; TPR repeat
      pfam13424
      Location:134 → 213
      TPR_12; Tetratricopeptide repeat

    2. NM_001415074.1 → NP_001402003.1  tetratricopeptide repeat protein 13 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A0G2JZ94, A0A8I6AC50

    3. NM_001415075.1 → NP_001402004.1  tetratricopeptide repeat protein 13 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      F1LR77

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      69534989..69589590 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039097660.2 → XP_038953588.1  tetratricopeptide repeat protein 13 isoform X3

      UniProtKB/TrEMBL
      F1LR77
      Conserved Domains (2) summary
      TIGR02917
      Location:104 → 372
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:203 → 231
      TPR; TPR repeat [structural motif]

    2. XM_006255803.5 → XP_006255865.1  tetratricopeptide repeat protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AC50
      Conserved Domains (3) summary
      sd00006
      Location:234 → 262
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:302 → 335
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:270 → 332
      TPR_11; TPR repeat

    3. XM_039097663.2 → XP_038953591.1  tetratricopeptide repeat protein 13 isoform X6

      UniProtKB/TrEMBL
      A6KJ14
      Conserved Domains (2) summary
      COG0457
      Location:71 → 238
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:172 → 202
      TPR; TPR repeat [structural motif]

    4. XM_039097662.2 → XP_038953590.1  tetratricopeptide repeat protein 13 isoform X5

      UniProtKB/TrEMBL
      A0A8I6ABT0, A6KJ14
      Related
      ENSRNOP00000090844.1, ENSRNOT00000113253.2
      Conserved Domains (2) summary
      COG0457
      Location:71 → 238
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:172 → 202
      TPR; TPR repeat [structural motif]

    5. XM_039097661.2 → XP_038953589.1  tetratricopeptide repeat protein 13 isoform X4

      UniProtKB/TrEMBL
      A6KJ14
      Conserved Domains (2) summary
      COG0457
      Location:129 → 275
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:176 → 204
      TPR; TPR repeat [structural motif]

    6. XM_017601247.3 → XP_017456736.1  tetratricopeptide repeat protein 13 isoform X2

      UniProtKB/TrEMBL
      A0A8I5YBY2, F1LR77
      Related
      ENSRNOP00000077631.1, ENSRNOT00000118767.2

    7. XM_039097664.2 → XP_038953592.1  tetratricopeptide repeat protein 13 isoform X7

      Conserved Domains (2) summary
      COG0457
      Location:2 → 97
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:1 → 26
      TPR; TPR repeat [structural motif]

    8. XM_039097665.2 → XP_038953593.1  tetratricopeptide repeat protein 13 isoform X8

      UniProtKB/TrEMBL
      Q3KR69
      Conserved Domains (1) summary
      sd00006
      Location:26 → 56
      TPR; TPR repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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