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    ZNF766 zinc finger protein 766 [ Homo sapiens (human) ]

    Gene ID: 90321, updated on 10-Dec-2024

    Summary

    Official Symbol
    ZNF766provided by HGNC
    Official Full Name
    zinc finger protein 766provided by HGNC
    Primary source
    HGNC:HGNC:28063
    See related
    Ensembl:ENSG00000196214 AllianceGenome:HGNC:28063
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis (RPKM 7.0), thyroid (RPKM 4.6) and 25 other tissues See more
    Orthologs
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    Genomic context

    See ZNF766 in Genome Data Viewer
    Location:
    19q13.41
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (52269587..52296046)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (55356777..55383229)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (52772840..52799299)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372449 Neighboring gene vomeronasal 1 receptor 99 pseudogene Neighboring gene uncharacterized LOC124904763 Neighboring gene Sharpr-MPRA regulatory region 2064 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15043 Neighboring gene vomeronasal 1 receptor 100 pseudogene Neighboring gene microRNA 643 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15044 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15045 Neighboring gene zinc finger protein 480 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:52841280-52841780 Neighboring gene zinc finger protein 610 Neighboring gene zinc finger protein 880

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in nucleus PubMed 
    is_active_in nucleus  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010851.3NP_001010851.1  zinc finger protein 766

      See identical proteins and their annotated locations for NP_001010851.1

      Status: VALIDATED

      Source sequence(s)
      AC010320, AK024268, BX648899
      Consensus CDS
      CCDS46163.1
      UniProtKB/Swiss-Prot
      B2RNE0, Q5HY98, Q7Z326
      Related
      ENSP00000409652.1, ENST00000439461.6
      Conserved Domains (5) summary
      smart00349
      Location:969
      KRAB; krueppel associated box
      COG5048
      Location:297457
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:357377
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:948
      KRAB; KRAB box
      pfam13465
      Location:397422
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      52269587..52296046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      55356777..55383229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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