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    Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307897, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sdr42e1provided by RGD
    Official Full Name
    short chain dehydrogenase/reductase family 42E, member 1provided by RGD
    Primary source
    RGD:1308481
    See related
    EnsemblRapid:ENSRNOG00000051819 AllianceGenome:RGD:1308481
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Hspc105; RGD1308481
    Summary
    Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in steroid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human SDR42E1 (short chain dehydrogenase/reductase family 42E, member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 127.9), Kidney (RPKM 18.5) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Sdr42e1 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (62624130..62636652, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (45715366..45727901, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (50207960..50220455, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene c-Maf-inducing protein Neighboring gene uncharacterized LOC102548350 Neighboring gene uncharacterized LOC120098622 Neighboring gene phospholipase C, gamma 2 Neighboring gene uncharacterized LOC120098492 Neighboring gene hydroxysteroid (17-beta) dehydrogenase 2 Neighboring gene M phase phosphoprotein 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    short-chain dehydrogenase/reductase family 42E member 1
    NP_001258198.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271269.1NP_001258198.1  short-chain dehydrogenase/reductase family 42E member 1

      See identical proteins and their annotated locations for NP_001258198.1

      Status: VALIDATED

      Source sequence(s)
      BI295943, BQ196592, FN798906, FQ103187, JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A0G2JT58, A0A8I6GEP8, A6IZH6
      Related
      ENSRNOP00000068579.2, ENSRNOT00000079760.3
      Conserved Domains (1) summary
      cl21454
      Location:10350
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      62624130..62636652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)