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    Cep95 centrosomal protein 95 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287766, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cep95provided by RGD
    Official Full Name
    centrosomal protein 95provided by RGD
    Primary source
    RGD:1309655
    See related
    EnsemblRapid:ENSRNOG00000014354 AllianceGenome:RGD:1309655
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc45; RGD1309655
    Summary
    Predicted to be located in centrosome. Predicted to be active in spindle pole. Orthologous to human CEP95 (centrosomal protein 95). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 141.0), Adrenal (RPKM 104.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cep95 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (92231829..92259813)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (91732111..91760095)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (94988362..95017774)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene DNA polymerase gamma 2, accessory subunit Neighboring gene microRNA 3064 Neighboring gene DEAD-box helicase 5 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 Neighboring gene transfer RNA alanine (anticodon AGC) 91 Neighboring gene survival of motor neuron-related-splicing factor 30-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in spindle pole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in spindle pole ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    centrosomal protein of 95 kDa
    Names
    centrosomal protein 95kDa
    coiled-coil domain containing 45
    coiled-coil domain-containing protein 45

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013862.1 → NP_001013884.1  centrosomal protein of 95 kDa

      See identical proteins and their annotated locations for NP_001013884.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083896
      UniProtKB/Swiss-Prot
      Q5XI03
      UniProtKB/TrEMBL
      A0A8I6AJA7, A6HK61
      Related
      ENSRNOP00000101297.1, ENSRNOT00000168710.1
      Conserved Domains (1) summary
      TIGR02168
      Location:578 → 809
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      92231829..92259813
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597144.3 → XP_017452633.1  centrosomal protein of 95 kDa isoform X1

      UniProtKB/TrEMBL
      A0A8I6AJA7, A0A8L2QW80
      Related
      ENSRNOP00000062563.3, ENSRNOT00000066525.4

    2. XM_063268755.1 → XP_063124825.1  centrosomal protein of 95 kDa isoform X2

    3. XM_039085634.2 → XP_038941562.1  centrosomal protein of 95 kDa isoform X4

      Conserved Domains (1) summary
      pfam19016
      Location:51 → 107
      DUF5745; Domain of unknown function (DUF5745)

    4. XM_039085633.2 → XP_038941561.1  centrosomal protein of 95 kDa isoform X3

      Conserved Domains (1) summary
      pfam19016
      Location:51 → 107
      DUF5745; Domain of unknown function (DUF5745)

    5. XM_063268756.1 → XP_063124826.1  centrosomal protein of 95 kDa isoform X5

    6. XM_039085635.2 → XP_038941563.1  centrosomal protein of 95 kDa isoform X6

      Conserved Domains (1) summary
      TIGR02168
      Location:198 → 433
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RNA

    1. XR_005489754.2 RNA Sequence

    2. XR_005489755.2 RNA Sequence

    3. XR_005489756.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XI03.1 GenPept UniProtKB/Swiss-Prot:Q5XI03

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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