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    Coa3 cytochrome C oxidase assembly factor 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498000, updated on 27-Nov-2024

    Summary

    Official Symbol
    Coa3provided by RGD
    Official Full Name
    cytochrome C oxidase assembly factor 3provided by RGD
    Primary source
    RGD:1564337
    See related
    EnsemblRapid:ENSRNOG00000020487 AllianceGenome:RGD:1564337
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc56; RGD1564337
    Summary
    Predicted to be involved in mitochondrial cytochrome c oxidase assembly and positive regulation of mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 14. Orthologous to human COA3 (cytochrome c oxidase assembly factor 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 369.3), Heart (RPKM 310.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Coa3 in Genome Data Viewer
    Location:
    10q31
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (86720454..86721435, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (86220192..86221173, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (89198750..89199731, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene vacuolar protein sorting 25 homolog Neighboring gene WNK lysine deficient protein kinase 4 Neighboring gene ATP synthase membrane subunit K, pseudogene 2 Neighboring gene cyclin N-terminal domain containing 1 Neighboring gene beclin 1 Neighboring gene proteasome activator subunit 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 56
    Names
    coiled-coil domain containing 56

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109047.1NP_001102517.1  coiled-coil domain-containing protein 56

      See identical proteins and their annotated locations for NP_001102517.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HJA1, D3Z9I1
      Related
      ENSRNOP00000027782.4, ENSRNOT00000027782.8
      Conserved Domains (1) summary
      pfam09813
      Location:9106
      Coiled-coil_56; Coiled-coil domain-containing protein 56

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      86720454..86721435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)