U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tef TEF transcription factor, PAR bZIP family member [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29362, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tefprovided by RGD
    Official Full Name
    TEF transcription factor, PAR bZIP family memberprovided by RGD
    Primary source
    RGD:3841
    See related
    EnsemblRapid:ENSRNOG00000019383 AllianceGenome:RGD:3841
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human TEF (TEF transcription factor, PAR bZIP family member). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 262.9), Muscle (RPKM 216.9) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tef in Genome Data Viewer
    Location:
    7q34
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (115197180..115221930)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (113317191..113341783)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (123033971..123058606)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene RAN GTPase activating protein 1 Neighboring gene zinc finger CCCH-type containing 7B Neighboring gene uncharacterized LOC134479944 Neighboring gene transducer of ERBB2, 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    thyrotroph embryonic factor
    Names
    TEF, PAR bZIP transcription factor
    thyrotrophic embryonic factor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019194.3NP_062067.2  thyrotroph embryonic factor

      See identical proteins and their annotated locations for NP_062067.2

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      P41224, Q3T1I8
      UniProtKB/TrEMBL
      A6HT20
      Related
      ENSRNOP00000026258.3, ENSRNOT00000026258.8
      Conserved Domains (1) summary
      cd14695
      Location:230288
      bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      115197180..115221930
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006242068.5XP_006242130.1  thyrotroph embryonic factor isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZT24
      Related
      ENSRNOP00000081617.2, ENSRNOT00000107707.2
      Conserved Domains (1) summary
      cd14695
      Location:214272
      bZIP_HLF; Basic leucine zipper (bZIP) domain of Hepatic leukemia factor (HLF) and similar proteins: a DNA-binding and dimerization domain
    2. XM_017594699.3XP_017450188.1  thyrotroph embryonic factor isoform X2

    3. XM_063263117.1XP_063119187.1  thyrotroph embryonic factor isoform X3

    4. XM_039078573.2XP_038934501.1  thyrotroph embryonic factor isoform X4