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    Fndc11 fibronectin type III domain containing 11 [ Mus musculus (house mouse) ]

    Gene ID: 332713, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fndc11provided by MGI
    Official Full Name
    fibronectin type III domain containing 11provided by MGI
    Primary source
    MGI:MGI:3051572
    See related
    Ensembl:ENSMUSG00000047841 AllianceGenome:MGI:3051572
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700026M20Rik
    Summary
    Orthologous to human FNDC11 (fibronectin type III domain containing 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 102.6) See more
    Orthologs
    human all
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    Genomic context

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    See Fndc11 in Genome Data Viewer
    Location:
    2 H4; 2 103.63 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (180854385..180864649)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181212592..181222856)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene PTK6 protein tyrosine kinase 6 Neighboring gene predicted gene, 40033 Neighboring gene src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites Neighboring gene STARR-positive B cell enhancer ABC_E4531 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene helicase with zinc finger 2, transcriptional coactivator Neighboring gene glucocorticoid modulatory element binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Clone Names

    • MGC58365

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    fibronectin type III domain-containing protein 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001379471.1 → NP_001366400.1  fibronectin type III domain-containing protein 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) repesents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AL450341, AL845506
      UniProtKB/TrEMBL
      A2AS00
      Conserved Domains (1) summary
      pfam17744
      Location:1 → 317
      DUF5581; Family of unknown function (DUF5581)

    2. NM_001379472.1 → NP_001366401.1  fibronectin type III domain-containing protein 11 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
      Source sequence(s)
      AL845506
      UniProtKB/TrEMBL
      A2AS00
      Related
      ENSMUSP00000104463.2, ENSMUST00000108835.2
      Conserved Domains (1) summary
      pfam17744
      Location:1 → 317
      DUF5581; Family of unknown function (DUF5581)

    3. NM_199312.5 → NP_955016.1  fibronectin type III domain-containing protein 11 isoform b

      See identical proteins and their annotated locations for NP_955016.1

      Status: VALIDATED

      Source sequence(s)
      AL845506
      Consensus CDS
      CCDS17205.1
      UniProtKB/Swiss-Prot
      A2AS01, Q80WB0
      Related
      ENSMUSP00000056320.7, ENSMUST00000050026.7
      Conserved Domains (1) summary
      pfam17744
      Location:1 → 317
      DUF5581; Family of unknown function (DUF5581)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      180854385..180864649
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011239949.3 → XP_011238251.1  fibronectin type III domain-containing protein 11 isoform X2

      See identical proteins and their annotated locations for XP_011238251.1

      UniProtKB/Swiss-Prot
      A2AS01, Q80WB0
      Conserved Domains (1) summary
      pfam17744
      Location:1 → 317
      DUF5581; Family of unknown function (DUF5581)

    2. XM_036162336.1 → XP_036018229.1  fibronectin type III domain-containing protein 11 isoform X1

      UniProtKB/TrEMBL
      A2AS00
      Conserved Domains (1) summary
      pfam17744
      Location:1 → 317
      DUF5581; Family of unknown function (DUF5581)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80WB0.1 GenPept UniProtKB/Swiss-Prot:Q80WB0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
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