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    Yipf2 Yip1 domain family, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 74766, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Yipf2provided by MGI
    Official Full Name
    Yip1 domain family, member 2provided by MGI
    Primary source
    MGI:MGI:1922016
    See related
    Ensembl:ENSMUSG00000032182 AllianceGenome:MGI:1922016
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1300010K09Rik
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi apparatus subcompartment and transport vesicle. Predicted to be active in Golgi apparatus. Orthologous to human YIPF2 (Yip1 domain family member 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 51.9), genital fat pad adult (RPKM 45.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Yipf2 in Genome Data Viewer
    Location:
    9 A3; 9 7.83 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21499978..21504131, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21588682..21592831, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene cDNA sequence AB124611 Neighboring gene STARR-positive B cell enhancer ABC_E11402 Neighboring gene STARR-positive B cell enhancer mm9_chr9:21350851-21351152 Neighboring gene coactivator-associated arginine methyltransferase 1 Neighboring gene predicted gene, 39303 Neighboring gene STARR-seq mESC enhancer starr_23505 Neighboring gene translocase of inner mitochondrial membrane 29 Neighboring gene predicted gene 7904 Neighboring gene microRNA 1946b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi medial cisterna ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi medial cisterna ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in Golgi trans cisterna ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi trans cisterna ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in trans-Golgi network ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in transport vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in transport vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein YIPF2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205157.1 → NP_001192086.1  protein YIPF2

      See identical proteins and their annotated locations for NP_001192086.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
      Source sequence(s)
      AC163748, AK133631, CD774249
      Consensus CDS
      CCDS22907.1
      UniProtKB/Swiss-Prot
      Q99LF3, Q99LP8
      Related
      ENSMUSP00000136463.2, ENSMUST00000180365.9
      Conserved Domains (1) summary
      pfam04893
      Location:84 → 245
      Yip1; Yip1 domain

    2. NM_001205158.1 → NP_001192087.1  protein YIPF2

      See identical proteins and their annotated locations for NP_001192087.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in both the 5' UTR and 3' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
      Source sequence(s)
      AC163748
      Consensus CDS
      CCDS22907.1
      UniProtKB/Swiss-Prot
      Q99LF3, Q99LP8
      Related
      ENSMUSP00000077649.8, ENSMUST00000078572.9
      Conserved Domains (1) summary
      pfam04893
      Location:84 → 245
      Yip1; Yip1 domain

    3. NM_001359298.1 → NP_001346227.1  protein YIPF2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 3' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
      Source sequence(s)
      AC163748
      Consensus CDS
      CCDS22907.1
      UniProtKB/Swiss-Prot
      Q99LF3, Q99LP8
      Conserved Domains (1) summary
      pfam04893
      Location:84 → 245
      Yip1; Yip1 domain

    4. NM_001359299.1 → NP_001346228.1  protein YIPF2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in both the 5' UTR and 3' UTR, compared to variant 1. Variants 1, 2, 3, 5 and 6 encode the same protein.
      Source sequence(s)
      AC163748
      Consensus CDS
      CCDS22907.1
      UniProtKB/Swiss-Prot
      Q99LF3, Q99LP8
      Conserved Domains (1) summary
      pfam04893
      Location:84 → 245
      Yip1; Yip1 domain

    5. NM_138303.2 → NP_612176.1  protein YIPF2

      See identical proteins and their annotated locations for NP_612176.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, 3, 5 and 6 encode the same protein.
      Source sequence(s)
      AC163748
      Consensus CDS
      CCDS22907.1
      UniProtKB/Swiss-Prot
      Q99LF3, Q99LP8
      Related
      ENSMUSP00000034700.8, ENSMUST00000034700.15
      Conserved Domains (1) summary
      pfam04893
      Location:84 → 245
      Yip1; Yip1 domain

    RNA

    1. NR_038062.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in both the 5' and 3' terminal exons, compared to variant 1. This variant is represented as non-coding because it lacks the translational start codon found in variant 1, and it does not contain any alternate open reading frames that are likely to result in a protein.
      Source sequence(s)
      AA967152, AK004959, CD774249
      Related
      ENSMUST00000213809.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      21499978..21504131 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242618.4 → XP_011240920.1  protein YIPF2 isoform X1

      See identical proteins and their annotated locations for XP_011240920.1

      UniProtKB/Swiss-Prot
      Q99LF3, Q99LP8
      Conserved Domains (1) summary
      pfam04893
      Location:84 → 245
      Yip1; Yip1 domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99LP8.1 GenPept UniProtKB/Swiss-Prot:Q99LP8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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