Nipsnap2 nipsnap homolog 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Nipsnap2provided by MGI
Official Full Name: nipsnap homolog 2provided by MGI
Primary source: MGI:MGI:1278343
See related: Ensembl:ENSMUSG00000029432 AllianceGenome:MGI:1278343
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gbas
Summary: Predicted to enable protein-macromolecule adaptor activity. Involved in mitophagy and positive regulation of high voltage-gated calcium channel activity. Located in cytoplasm. Is expressed in olfactory cortex ventricular layer; rest of cerebellum ventricular layer; and telencephalon ventricular layer. Orthologous to human NIPSNAP2 (nipsnap homolog 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in heart adult (RPKM 142.2), cerebellum adult (RPKM 27.2) and 21 other tissues See more
Orthologs: human all
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Genomic context

Location:: 5 G1.3; 5 68.26 cM

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (129802080..129835391)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (129725016..129758327)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

[Comparative clinical data on the bronchodilating effect of some selective beta-2 stimulating drugs].", trans "Rilievi clinici comparativi sull'effetto broncodilatatore di alcuni farmaci beta-2 stimolanti selettivi.
Title: [Comparative clinical data on the bronchodilating effect of some selective beta-2 stimulating drugs].

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH137104 (e-PCR)
- UniSTS:219192

AV006093 (e-PCR)
- UniSTS:179276

AJ001261 (e-PCR)
- UniSTS:159450

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables protein-macromolecule adaptor activity	ISO Inferred from Sequence Orthology more info
enables protein-macromolecule adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in mitochondrion organization	ISO Inferred from Sequence Orthology more info
involved_in mitophagy	IDA Inferred from Direct Assay more info	PubMed
involved_in mitophagy	ISO Inferred from Sequence Orthology more info
involved_in oxidative phosphorylation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of high voltage-gated calcium channel activity	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in mitochondrial matrix	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: protein NipSnap homolog 2

Names: glioblastoma amplified sequence

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.