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    Phldb3 pleckstrin homology like domain, family B, member 3 [ Mus musculus (house mouse) ]

    Gene ID: 232970, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Phldb3provided by MGI
    Official Full Name
    pleckstrin homology like domain, family B, member 3provided by MGI
    Primary source
    MGI:MGI:3642959
    See related
    Ensembl:ENSMUSG00000074277 AllianceGenome:MGI:3642959
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm10102; EG232970
    Summary
    Predicted to enable enzyme binding activity. Orthologous to human PHLDB3 (pleckstrin homology like domain family B member 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in placenta adult (RPKM 3.5), stomach adult (RPKM 3.2) and 20 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Phldb3 in Genome Data Viewer
    Location:
    7 A3; 7 11.8 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (24309731..24328722)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24610294..24629297)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18269 Neighboring gene X-ray repair complementing defective repair in Chinese hamster cells 1 Neighboring gene zinc finger protein 575 Neighboring gene ethylmalonic encephalopathy 1 Neighboring gene STARR-seq mESC enhancer starr_18271 Neighboring gene STARR-positive B cell enhancer ABC_E4903 Neighboring gene predicted gene, 26550 Neighboring gene Ly6/Plaur domain containing 3 Neighboring gene predicted gene 4598

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    pleckstrin homology-like domain family B member 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102613.1 → NP_001096083.1  pleckstrin homology-like domain family B member 3

      See identical proteins and their annotated locations for NP_001096083.1

      Status: PROVISIONAL

      Source sequence(s)
      AC161166
      Consensus CDS
      CCDS52139.1
      UniProtKB/TrEMBL
      E9QAF4
      Related
      ENSMUSP00000073047.6, ENSMUST00000073325.6
      Conserved Domains (2) summary
      cd14673
      Location:543 → 643
      PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
      TIGR02168
      Location:112 → 326
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      24309731..24328722
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322157.3 → XP_017177646.1  pleckstrin homology-like domain family B member 3 isoform X2

      UniProtKB/TrEMBL
      E9QAF4
      Conserved Domains (2) summary
      cd14673
      Location:543 → 643
      PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
      TIGR02168
      Location:112 → 326
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. XM_030242440.2 → XP_030098300.1  pleckstrin homology-like domain family B member 3 isoform X1

      Conserved Domains (1) summary
      TIGR02168
      Location:112 → 326
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_030242441.2 → XP_030098301.1  pleckstrin homology-like domain family B member 3 isoform X1

      Conserved Domains (1) summary
      TIGR02168
      Location:112 → 326
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    Nucleotide Protein Strain
    Heading Accession and Version

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