4933427D14Rik RIKEN cDNA 4933427D14 gene [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: 4933427D14Rikprovided by MGI
Official Full Name: RIKEN cDNA 4933427D14 geneprovided by MGI
Primary source: MGI:MGI:1921727
See related: Ensembl:ENSMUSG00000020807 Ensembl:ENSMUSG00000107877 AllianceGenome:MGI:1921727
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: MNR; Gm43951; Kiaa0753
Summary: Predicted to be involved in cytosolic ciliogenesis and protein localization to centrosome. Predicted to be located in centrosome and cytosol. Predicted to be active in centriolar satellite. Is expressed in several structures, including alimentary system; brain; egg cylinder; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in Joubert syndrome; asphyxiating thoracic dystrophy; and orofaciodigital syndrome. Orthologous to human KIAA0753 (KIAA0753). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in CNS E18 (RPKM 7.6), CNS E14 (RPKM 7.5) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11; 11 B4

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (72044755..72098308, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (72153929..72207482, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

KIAA0753 enhances osteoblast differentiation suppressed by diabetes.
Title: KIAA0753 enhances osteoblast differentiation suppressed by diabetes.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2)

General gene information

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Markers

RH127127 (e-PCR)
- UniSTS:208700

22.MMHAP12FRH7.seq (e-PCR)
- UniSTS:123555

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in centriole replication	IEA Inferred from Electronic Annotation more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in cytosolic ciliogenesis	ISO Inferred from Sequence Orthology more info
involved_in cytosolic ciliogenesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein localization to centrosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to centrosome	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in centriolar satellite	IBA Inferred from Biological aspect of Ancestor more info
located_in centriolar satellite	IEA Inferred from Electronic Annotation more info
located_in centriolar satellite	ISO Inferred from Sequence Orthology more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in microtubule organizing center	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein moonraker

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.