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    ZNF705A zinc finger protein 705A [ Homo sapiens (human) ]

    Gene ID: 440077, updated on 27-Nov-2024

    Summary

    Official Symbol
    ZNF705Aprovided by HGNC
    Official Full Name
    zinc finger protein 705Aprovided by HGNC
    Primary source
    HGNC:HGNC:32281
    See related
    Ensembl:ENSG00000196946 AllianceGenome:HGNC:32281
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See ZNF705A in Genome Data Viewer
    Location:
    12p13.31
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (8157015..8180046)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (8170619..8193651)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (8309611..8332642)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 4 member A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:8286281-8287059 Neighboring gene POU class 5 homeobox 1 pseudogene 3 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr12:8294369-8294870 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:8296489-8296988 Neighboring gene GCSH pseudogene 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5930 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:8333169-8333668 Neighboring gene family with sequence similarity 66 member C Neighboring gene defensin beta 109F (pseudogene) Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr12:8375857-8377056 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5931 Neighboring gene family with sequence similarity 90 member A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004328.3NP_001004328.1  zinc finger protein 705A

      See identical proteins and their annotated locations for NP_001004328.1

      Status: VALIDATED

      Source sequence(s)
      AC092111
      Consensus CDS
      CCDS31737.1
      UniProtKB/Swiss-Prot
      Q6ZN79
      Related
      ENSP00000379816.4, ENST00000396570.8
      Conserved Domains (5) summary
      smart00349
      Location:766
      KRAB; krueppel associated box
      COG5048
      Location:121300
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:174194
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:746
      KRAB; KRAB box
      pfam13465
      Location:214239
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      8157015..8180046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      8170619..8193651
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)