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    Faim Fas apoptotic inhibitory molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 140930, updated on 27-Nov-2024

    Summary

    Official Symbol
    Faimprovided by RGD
    Official Full Name
    Fas apoptotic inhibitory moleculeprovided by RGD
    Primary source
    RGD:620572
    See related
    EnsemblRapid:ENSRNOG00000030069 AllianceGenome:RGD:620572
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of neurogenesis. Predicted to be located in cytoplasm. Orthologous to human FAIM (Fas apoptotic inhibitory molecule). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 39.5), Kidney (RPKM 38.1) and 9 other tissues See more
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    Genomic context

    See Faim in Genome Data Viewer
    Location:
    8q31
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (108423259..108445365)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (99543877..99569499)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (107225119..107247228)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547261 Neighboring gene forkhead box L2 Neighboring gene coxsackie virus and adenovirus receptor-like 1 Neighboring gene phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    fas apoptotic inhibitory molecule 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_080895.2NP_543171.1  fas apoptotic inhibitory molecule 1

      See identical proteins and their annotated locations for NP_543171.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6I2C3
      Related
      ENSRNOP00000049149.3, ENSRNOT00000047613.6
      Conserved Domains (1) summary
      pfam06905
      Location:3174
      FAIM1; Fas apoptotic inhibitory molecule (FAIM1)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      108423259..108445365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017596121.3XP_017451610.1  fas apoptotic inhibitory molecule 1 isoform X2

    2. XM_002729959.6XP_002730005.1  fas apoptotic inhibitory molecule 1 isoform X1

      See identical proteins and their annotated locations for XP_002730005.1

      UniProtKB/Swiss-Prot
      Q8R5H8, Q8VHR4
      UniProtKB/TrEMBL
      A6I2C2
      Related
      ENSRNOP00000039749.2, ENSRNOT00000045821.5
    3. XM_006243611.5XP_006243673.1  fas apoptotic inhibitory molecule 1 isoform X1

      See identical proteins and their annotated locations for XP_006243673.1

      UniProtKB/Swiss-Prot
      Q8R5H8, Q8VHR4
      UniProtKB/TrEMBL
      A6I2C2
    4. XM_063264801.1XP_063120871.1  fas apoptotic inhibitory molecule 1 isoform X3

      UniProtKB/TrEMBL
      A6I2C3