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    Rida reactive intermediate imine deaminase A homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 65151, updated on 3-Dec-2024

    Summary

    Official Symbol
    Ridaprovided by RGD
    Official Full Name
    reactive intermediate imine deaminase A homologprovided by RGD
    Primary source
    RGD:70940
    See related
    AllianceGenome:RGD:70940
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Psp; PSP1; L-PSP; Hrsp12; rp14.5
    Summary
    Enables several functions, including RNA endonuclease activity, producing 3'-phosphomonoesters; identical protein binding activity; and long-chain fatty acid binding activity. Involved in several processes, including G1 to G0 transition; negative regulation of translation; and response to salt. Located in cytosol; mitochondrial matrix; and peroxisome. Orthologous to human RIDA (reactive intermediate imine deaminase A homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 11218.5), Liver (RPKM 6497.6) and 1 other tissue See more
    Orthologs
    NEW
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    Genomic context

    See Rida in Genome Data Viewer
    Location:
    7q22
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (67576586..67590493, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (65691429..65705257, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (73256506..73270308, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA72 Neighboring gene ribosomal protein L30 Neighboring gene glutamate-rich 5 Neighboring gene POP1 homolog, ribonuclease P/MRP subunit Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 2-iminobutanoate deaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables 2-iminopropanoate deaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA endonuclease activity, producing 3'-phosphomonoesters IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables cation binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables deaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables long-chain fatty acid binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transition metal ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G1 to G0 transition IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in kidney development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in lung development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in mRNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mRNA destabilization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA destabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA destabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of translation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to lipid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to salt IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrial matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    2-iminobutanoate/2-iminopropanoate deaminase
    Names
    14.5 kDa translational inhibitor protein
    UK114 antigen homolog
    heat-responsive protein 12
    liver perchloric acid-soluble protein
    perchloric acid-soluble protein
    perchrolic acid soluble protein
    ribonuclease UK114
    translation inhibitor L-PSP ribonuclease
    NP_113902.2
    XP_063120287.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031714.2NP_113902.2  2-iminobutanoate/2-iminopropanoate deaminase

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      O35262, P52759, Q9WUV8
      UniProtKB/TrEMBL
      A6HR02
      Conserved Domains (1) summary
      TIGR00004
      Location:6129
      TIGR00004; reactive intermediate/imine deaminase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      67576586..67590493 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264217.1XP_063120287.1  2-iminobutanoate/2-iminopropanoate deaminase isoform X1

      UniProtKB/TrEMBL
      A0A8L2Q359