U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Fam219a family with sequence similarity 219, member A [ Mus musculus (house mouse) ]

    Gene ID: 71901, updated on 27-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Fam219aprovided by MGI
    Official Full Name
    family with sequence similarity 219, member Aprovided by MGI
    Primary source
    MGI:MGI:1919151
    See related
    Ensembl:ENSMUSG00000028439 AllianceGenome:MGI:1919151
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310028H24Rik
    Summary
    Orthologous to human FAM219A (family with sequence similarity 219 member A). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in frontal lobe adult (RPKM 23.8), cortex adult (RPKM 22.6) and 25 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Fam219a in Genome Data Viewer
    Location:
    4 A5; 4 21.71 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (41517691..41569538, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (41517691..41569607, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene myogenesis regulating glycosidase (putative) Neighboring gene sperm microtubule inner protein 6 Neighboring gene family with sequence similarity 219, member A, opposite strand Neighboring gene predicted gene 12404 Neighboring gene STARR-positive B cell enhancer ABC_E659 Neighboring gene dynein axonemal intermediate chain 1 Neighboring gene STARR-seq mESC enhancer starr_10035 Neighboring gene predicted gene 12405 Neighboring gene energy homeostasis associated

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein FAM219A
    Names
    likely ortholog of H. sapiens chromosome 9 open reading frame 25 (C9orf25)
    uncharacterized protein C9orf25 homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159583.2 → NP_001153055.1  protein FAM219A isoform 1

      See identical proteins and their annotated locations for NP_001153055.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AL831723
      Consensus CDS
      CCDS51141.1
      UniProtKB/TrEMBL
      A2ANP1
      Related
      ENSMUSP00000103687.4, ENSMUST00000108052.10
      Conserved Domains (1) summary
      pfam15260
      Location:37 → 167
      FAM219A; Protein family FAM219A

    2. NM_001377101.1 → NP_001364030.1  protein FAM219A isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL831723
      Conserved Domains (1) summary
      pfam15260
      Location:54 → 181
      FAM219A; Protein family FAM219A

    3. NM_001377102.1 → NP_001364031.1  protein FAM219A isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) encodes the longest isoform (3).
      Source sequence(s)
      AL831723
      Conserved Domains (1) summary
      pfam15260
      Location:54 → 182
      FAM219A; Protein family FAM219A

    4. NM_001377103.1 → NP_001364032.1  protein FAM219A isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL831723
      Conserved Domains (1) summary
      pfam15260
      Location:43 → 170
      FAM219A; Protein family FAM219A

    5. NM_001377104.1 → NP_001364033.1  protein FAM219A isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL831723, BC172173
      UniProtKB/TrEMBL
      B7ZWP1
      Conserved Domains (1) summary
      pfam15260
      Location:37 → 164
      FAM219A; Protein family FAM219A

    6. NM_001377105.1 → NP_001364034.1  protein FAM219A isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL831723
      UniProtKB/TrEMBL
      A2ANP2
      Related
      ENSMUSP00000103685.2, ENSMUST00000108050.2
      Conserved Domains (1) summary
      pfam15260
      Location:26 → 153
      FAM219A; Protein family FAM219A

    7. NM_027993.4 → NP_082269.2  protein FAM219A isoform 2

      See identical proteins and their annotated locations for NP_082269.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, which results in a protein (isoform 2) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AL831723
      Consensus CDS
      CCDS38718.1
      UniProtKB/Swiss-Prot
      A2ANP3, Q9D772
      Related
      ENSMUSP00000103684.3, ENSMUST00000108049.9
      Conserved Domains (1) summary
      pfam15260
      Location:26 → 156
      FAM219A; Protein family FAM219A

    RNA

    1. NR_165081.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL831723

    2. NR_165082.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL831723

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      41517691..41569538 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D772.2 GenPept UniProtKB/Swiss-Prot:Q9D772

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools