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    Acte1 actin, epsilon 1 [ Mus musculus (house mouse) ]

    Gene ID: 102636989, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Acte1provided by MGI
    Official Full Name
    actin, epsilon 1provided by MGI
    Primary source
    MGI:MGI:2685344
    See related
    Ensembl:ENSMUSG00000031085 AllianceGenome:MGI:2685344
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm498
    Summary
    Predicted to be active in actin cytoskeleton. Orthologous to human ACTE1P (actin epsilon 1, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 58.2) See more
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    Genomic context

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    See Acte1 in Genome Data Viewer
    Location:
    7 F5; 7 88.33 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (143420575..143453780)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (143866838..143900044)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene NAD synthetase 1 Neighboring gene STARR-positive B cell enhancer ABC_E1750 Neighboring gene STARR-positive B cell enhancer ABC_E2257 Neighboring gene STARR-positive B cell enhancer ABC_E3763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:151023918-151024190 Neighboring gene 7-dehydrocholesterol reductase Neighboring gene STARR-seq mESC enhancer starr_20537 Neighboring gene microRNA 6404 Neighboring gene predicted gene, 34445

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of postsynaptic actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in axonogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in actin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    actin, epsilon 1
    Names
    actin-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001369834.1 → NP_001356763.1  actin, epsilon 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC133502
      UniProtKB/TrEMBL
      J3QK70
      Conserved Domains (1) summary
      cl17037
      Location:2 → 382
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    2. NM_001369835.1 → NP_001356764.1  actin, epsilon 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC133502
      Consensus CDS
      CCDS90361.1
      UniProtKB/TrEMBL
      D3YYH9, J3QK70
      Related
      ENSMUSP00000115809.2, ENSMUST00000152910.3
      Conserved Domains (1) summary
      cl17037
      Location:2 → 372
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    3. NM_001369836.1 → NP_001356765.1  actin, epsilon 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC133502
      Consensus CDS
      CCDS90360.1
      UniProtKB/TrEMBL
      A0A140LHA3, J3QK70
      Related
      ENSMUSP00000146335.2, ENSMUST00000207630.2
      Conserved Domains (1) summary
      cl17037
      Location:2 → 370
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    4. NM_001369837.1 → NP_001356766.1  actin, epsilon 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC133502
      UniProtKB/TrEMBL
      J3QK70
      Conserved Domains (1) summary
      cl17037
      Location:3 → 308
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      143420575..143453780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030241966.1 → XP_030097826.1  actin, epsilon 1 isoform X4

      Conserved Domains (1) summary
      cl17037
      Location:2 → 216
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    2. XM_006508669.5 → XP_006508732.1  actin, epsilon 1 isoform X2

      UniProtKB/TrEMBL
      J3QK70
      Conserved Domains (1) summary
      cl17037
      Location:2 → 275
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    3. XM_030241967.1 → XP_030097827.1  actin, epsilon 1 isoform X4

      Conserved Domains (1) summary
      cl17037
      Location:2 → 216
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    4. XM_006508666.1 → XP_006508729.1  actin, epsilon 1 isoform X1

      UniProtKB/TrEMBL
      J3QK70
      Conserved Domains (1) summary
      cl17037
      Location:2 → 380
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    5. XM_030241965.1 → XP_030097825.1  actin, epsilon 1 isoform X4

      Conserved Domains (1) summary
      cl17037
      Location:2 → 216
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    6. XM_030241964.1 → XP_030097824.1  actin, epsilon 1 isoform X3

      Conserved Domains (1) summary
      cl17037
      Location:1 → 256
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    7. XM_006508671.2 → XP_006508734.1  actin, epsilon 1 isoform X4

      See identical proteins and their annotated locations for XP_006508734.1

      Conserved Domains (1) summary
      cl17037
      Location:2 → 216
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    8. XM_006508672.4 → XP_006508735.1  actin, epsilon 1 isoform X4

      See identical proteins and their annotated locations for XP_006508735.1

      Conserved Domains (1) summary
      cl17037
      Location:2 → 216
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    Nucleotide Protein
    Heading Accession and Version

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