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    H2bc26 H2B clustered histone 26 [ Mus musculus (house mouse) ]

    Gene ID: 382522, updated on 27-Nov-2024

    Summary

    Official Symbol
    H2bc26provided by MGI
    Official Full Name
    H2B clustered histone 26provided by MGI
    Primary source
    MGI:MGI:1922442
    See related
    Ensembl:ENSMUSG00000080712 AllianceGenome:MGI:1922442
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H2bu1; H2bu1-ps; H2bc26-ps; Hist3h2bb; 4933432H21; B2Hist3h2bb; Hist3h2bb-ps; 4930534G10Rik
    Summary
    Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2b family. [provided by RefSeq, Feb 2021]
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    Genomic context

    See H2bc26 in Genome Data Viewer
    Location:
    11 B1.3; 11 36.38 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58842961..58845278, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58954048..58954512, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 187 Neighboring gene predicted gene, 51864 Neighboring gene STARR-positive B cell enhancer ABC_E3954 Neighboring gene H2B clustered histone 27 Neighboring gene STARR-positive B cell enhancer ABC_E114 Neighboring gene H2A clustered histone 25 Neighboring gene tripartite motif-containing 17 Neighboring gene STARR-positive B cell enhancer ABC_E5230 Neighboring gene STARR-positive B cell enhancer ABC_E6989 Neighboring gene H3.4 histone, cluster member

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC130256

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone H2B type 3-B
    Names
    H2B.U histone 1, pseudogene
    histone 3, H2bb
    histone cluster 3, H2bb, pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001393523.1NP_001380452.1  histone H2B type 3-B

      Status: VALIDATED

      Source sequence(s)
      AL662809
      UniProtKB/Swiss-Prot
      Q3B7Z7, Q8CGP0
      UniProtKB/TrEMBL
      A0JLV3
      Related
      ENSMUSP00001091675.1, ENSMUST00000117558.3
      Conserved Domains (1) summary
      smart00427
      Location:36124
      H2B; Histone H2B

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      58842961..58845278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_134309.1: Suppressed sequence

      Description
      NR_134309.1: This RefSeq was removed because it is now thought that this gene does encode a protein.