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    CHST7 carbohydrate sulfotransferase 7 [ Homo sapiens (human) ]

    Gene ID: 56548, updated on 10-Dec-2024

    Summary

    Official Symbol
    CHST7provided by HGNC
    Official Full Name
    carbohydrate sulfotransferase 7provided by HGNC
    Primary source
    HGNC:HGNC:13817
    See related
    Ensembl:ENSG00000147119 MIM:300375; AllianceGenome:HGNC:13817
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GST-5; C6ST-2
    Summary
    This gene is a member of the Gal/GalNAc/GlcNAc (galactose/N-acetylgalactosamine/N-acetylglucosamine) 6-O-sulfotransferase (GST) family. Members of this family encode enzymes that catalyze the specific addition of sulfate groups to distinct hydroxyl and amino groups of carbohydrates. The encoded protein catalyzes the sulfation of 6-hydroxyl group of GalNAc in chondroitin. [provided by RefSeq, Aug 2013]
    Expression
    Broad expression in spleen (RPKM 5.5), fat (RPKM 5.1) and 22 other tissues See more
    Orthologs
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    Genomic context

    See CHST7 in Genome Data Viewer
    Location:
    Xp11.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (46573765..46598496)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (45980734..46005466)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (46433200..46457931)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:46404230-46405429 Neighboring gene ZNF674 antisense RNA 1 (head to head) Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:46411040-46411938 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29571 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20790 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20791 Neighboring gene marker of proliferation Ki-67 pseudogene 1 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chrX:46447043-46447647 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:46447648-46448251 Neighboring gene uncharacterized LOC124905182 Neighboring gene solute carrier family 9 member A7 Neighboring gene phosphoglycerate mutase 1 pseudogene 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp160, precursor env Sulfate is linked to the carbohydrate chains of HIV-1 glycoproteins gp160, gp120, and gp41 during the endoplasmic reticulum to Golgi transport of the glycoproteins PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    General gene information

    Potential readthrough

    Included gene: KRBOX4

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in Golgi membrane  
    located_in membrane PubMed 
    located_in membrane PubMed 

    General protein information

    Preferred Names
    carbohydrate sulfotransferase 7
    Names
    N-acetylglucosamine 6-O-sulfotransferase 4
    carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
    chondroitin 6-sulfotransferase-2
    galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5
    glcNAc6ST-4
    gn6st-4
    NP_063939.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029799.1 RefSeqGene

      Range
      5009..29740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_019886.4 → NP_063939.2  carbohydrate sulfotransferase 7

      See identical proteins and their annotated locations for NP_063939.2

      Status: REVIEWED

      Source sequence(s)
      AB037187, BC045537, BP250418, DA155923, DA277492
      Consensus CDS
      CCDS14268.1
      UniProtKB/Swiss-Prot
      O75667, Q9NS84
      Related
      ENSP00000276055.3, ENST00000276055.4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      46573765..46598496
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      45980734..46005466
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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