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    LINC00326 long intergenic non-protein coding RNA 326 [ Homo sapiens (human) ]

    Gene ID: 285735, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00326provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 326provided by HGNC
    Primary source
    HGNC:HGNC:41926
    See related
    Ensembl:ENSG00000231023 AllianceGenome:HGNC:41926
    Gene type
    ncRNA
    RefSeq status
    PREDICTED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NCRNA00326
    Expression
    Restricted expression toward testis (RPKM 4.9) See more
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    Genomic context

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    See LINC00326 in Genome Data Viewer
    Location:
    6q23.2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (133088080..133106578)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (134277003..134295501)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (133409219..133427717)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378008 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:133308297-133309496 Neighboring gene ribosomal protein L23a pseudogene 46 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_89898 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_89904 Neighboring gene MT-CYB pseudogene 4 Neighboring gene serine/arginine repetitive matrix protein 1-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:133562838-133563732 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:133563733-133564625 Neighboring gene EYA transcriptional coactivator and phosphatase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis. Zhang Y, et al. Biol Direct, 2023 Feb 6. PMID 36747258, Free PMC Article
    2. CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism. Søndergaard JN, et al. Gut, 2022 Jan 12. PMID 35022268, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/beta-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis.
      Title: Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • MGC126751, MGC126753

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_026969.1 RNA Sequence

      Status: PREDICTED

      Source sequence(s)
      AL591115, BC039371, BC101702, BI460768
      Related
      ENST00000665546.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      133088080..133106578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      134277003..134295501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001037231.1: Suppressed sequence

      Description
      NM_001037231.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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