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    stx2B Shiga toxin 2 subunit B [ Escherichia coli O157:H7 str. Sakai ]

    Gene ID: 912579, updated on 6-Oct-2023

    Summary

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    Gene symbol
    stx2B
    Gene description
    Shiga toxin 2 subunit B
    Locus tag
    ECs_1206
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli O157:H7 str. Sakai (strain: Sakai, substrain: RIMD 0509952, serovar: O157:H7)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
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    Genomic context

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    Sequence:
    NC_002695.2 (1268078..1268347)

    NC_002695.2Genomic Context describing neighboring genes Neighboring gene tRNA-Arg Neighboring gene Shiga toxin 2 subunit A Neighboring gene hypothetical protein Neighboring gene IS629 transposase OrfB Neighboring gene IS629 transposase OrfA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002695.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The serine 31 residue of the B subunit of Shiga toxin 2 is essential for secretion in enterohemorrhagic Escherichia coli. Shimizu T, et al. Infect Immun, 2007 May. PMID 17325057, Free PMC Article
    2. Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction. Kulczyk AW, et al. J Biol Chem, 2023 Jan. PMID 36528064, Free PMC Article
    3. Comparative analysis of the whole set of rRNA operons between an enterohemorrhagic Escherichia coli O157:H7 Sakai strain and an Escherichia coli K-12 strain MG1655. Ohnishi M, et al. Syst Appl Microbiol, 2000 Oct. PMID 11108008
    4. Complete nucleotide sequence of the prophage VT2-Sakai carrying the verotoxin 2 genes of the enterohemorrhagic Escherichia coli O157:H7 derived from the Sakai outbreak. Makino K, et al. Genes Genet Syst, 1999 Oct. PMID 10734605
    5. Complete nucleotide sequence of the prophage VT1-Sakai carrying the Shiga toxin 1 genes of the enterohemorrhagic Escherichia coli O157:H7 strain derived from the Sakai outbreak. Yokoyama K, et al. Gene, 2000 Nov 27. PMID 11111050

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction.
      Title: Cryo-EM structure of Shiga toxin 2 in complex with the native ribosomal P-stalk reveals residues involved in the binding interaction.
    2. These results indicate that the serine 31 residue of the B subunit of Stx2 contains secretion-related information.
      Title: The serine 31 residue of the B subunit of Shiga toxin 2 is essential for secretion in enterohemorrhagic Escherichia coli.
    Submit: New GeneRIF Correction

    General protein information

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    Preferred Names
    Shiga toxin 2 subunit B

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002695.2 Reference assembly

      Range
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_309233.1 Shiga toxin 2 subunit B [Escherichia coli O157:H7 str. Sakai]

      See identical proteins and their annotated locations for NP_309233.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A6MTR2, A6MTT2, A6MTU0, Q8KU15, Q9RHP4, Q9RHP7, Q9RHP8
      Conserved Domains (1) summary
      pfam02258
      Location:21 → 86
      SLT_beta; Shiga-like toxin beta subunit
    Nucleotide Protein
    Heading Accession and Version

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