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    Tmem19 transmembrane protein 19 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299800, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tmem19provided by RGD
    Official Full Name
    transmembrane protein 19provided by RGD
    Primary source
    RGD:735209
    See related
    EnsemblRapid:ENSRNOG00000003985 AllianceGenome:RGD:735209
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be active in membrane. Orthologous to human TMEM19 (transmembrane protein 19). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 75.3), Adrenal (RPKM 52.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem19 in Genome Data Viewer
    Location:
    7q22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (52844985..52871708, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (50958884..50985601, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (58316583..58343761, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 15 Neighboring gene uncharacterized LOC134479691 Neighboring gene RAB21, member RAS oncogene family Neighboring gene THAP domain containing 2 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene zinc finger, C3H1-type containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC72591

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199098.2 → NP_954529.2  transmembrane protein 19

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/Swiss-Prot
      Q6P726
      UniProtKB/TrEMBL
      A0A0G2K7B8, A6IGK6, A6IGK7
      Related
      ENSRNOP00000074140.2, ENSRNOT00000090560.3
      Conserved Domains (1) summary
      pfam01940
      Location:68 → 322
      DUF92; Integral membrane protein DUF92

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      52844985..52871708 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241347.5 → XP_006241409.1  transmembrane protein 19 isoform X1

      UniProtKB/Swiss-Prot
      Q6P726
      UniProtKB/TrEMBL
      A0A0H2UHC5, A6IGK6
      Related
      ENSRNOP00000005310.6, ENSRNOT00000005310.6
      Conserved Domains (1) summary
      pfam01940
      Location:82 → 334
      DUF92; Integral membrane protein DUF92

    2. XM_006241348.5 → XP_006241410.1  transmembrane protein 19 isoform X2

      See identical proteins and their annotated locations for XP_006241410.1

      UniProtKB/Swiss-Prot
      Q6P726
      UniProtKB/TrEMBL
      A0A0G2K7B8, A6IGK6, A6IGK7
      Conserved Domains (1) summary
      pfam01940
      Location:68 → 322
      DUF92; Integral membrane protein DUF92
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P726.2 GenPept UniProtKB/Swiss-Prot:Q6P726

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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