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    Or4k36 olfactory receptor family 4 subfamily K member 36 [ Mus musculus (house mouse) ]

    Gene ID: 258910, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Or4k36provided by MGI
    Official Full Name
    olfactory receptor family 4 subfamily K member 36provided by MGI
    Primary source
    MGI:MGI:3031114
    See related
    Ensembl:ENSMUSG00000109449 AllianceGenome:MGI:3031114
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOR248-1; Olfr1280
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or4k36 in Genome Data Viewer
    Location:
    2 E3; 2 56.75 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (111144295..111204476)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (111313950..111374131)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily F member 54 Neighboring gene olfactory receptor family 4 subfamily G member 16 Neighboring gene olfactory receptor family 4 subfamily K member 37 Neighboring gene olfactory receptor family 4 subfamily K member 38 Neighboring gene olfactory receptor family 4 subfamily K member 77 Neighboring gene olfactory receptor family 4 subfamily G member 17 Neighboring gene olfactory receptor family 4 subfamily K member 39

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Analysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypes. Favor J, et al. Genetics, 2009 Aug. PMID 19474196, Free PMC Article
    2. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    3. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    4. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article
    5. A unified nomenclature for vertebrate olfactory receptors. Olender T, et al. BMC Evol Biol, 2020 Apr 15. PMID 32295537, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    olfactory receptor family 4 subfamily K member 36
    Names
    GA_x6K02T2Q125-72366920-72367837
    olfactory receptor 1280
    olfactory receptor MOR248-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146908.1 → NP_667119.1  olfactory receptor family 4 subfamily K member 36

      See identical proteins and their annotated locations for NP_667119.1

      Status: PROVISIONAL

      Source sequence(s)
      AY073180
      Consensus CDS
      CCDS16520.1
      UniProtKB/TrEMBL
      A0A0N4SWF1, Q8VGG8
      Related
      ENSMUSP00000080805.4, ENSMUST00000082167.5
      Conserved Domains (1) summary
      cd15226
      Location:25 → 291
      7tmA_OR4-like; olfactory receptor family 4 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      111144295..111204476
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499567.1 → XP_006499630.1  olfactory receptor family 4 subfamily K member 36 isoform X1

      See identical proteins and their annotated locations for XP_006499630.1

      UniProtKB/TrEMBL
      A0A0N4SWF1, Q8VGG8
      Related
      ENSMUSP00000151980.2, ENSMUST00000219291.2
      Conserved Domains (1) summary
      cd15226
      Location:25 → 291
      7tmA_OR4-like; olfactory receptor family 4 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RNA

    1. XR_001782758.1 RNA Sequence

    2. XR_866283.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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