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    NPIPB9 nuclear pore complex interacting protein family member B9 [ Homo sapiens (human) ]

    Gene ID: 100507607, updated on 10-Dec-2024

    Summary

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    Official Symbol
    NPIPB9provided by HGNC
    Official Full Name
    nuclear pore complex interacting protein family member B9provided by HGNC
    Primary source
    HGNC:HGNC:41987
    See related
    Ensembl:ENSG00000196993 AllianceGenome:HGNC:41987
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 11.3), skin (RPKM 4.2) and 25 other tissues See more
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    Genomic context

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    See NPIPB9 in Genome Data Viewer
    Location:
    16p11.2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (28751787..28772864)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (29016081..29053452)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (28763108..28784185)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3 subunit C Neighboring gene microRNA 6862-2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:28742791-28743343 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:28751627-28752170 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:28752171-28752713 Neighboring gene uncharacterized LOC124903761 Neighboring gene pro-apoptotic WT1 regulator pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:28770347-28770847 Neighboring gene phospholipase A2 group XK, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:28791989-28792628 Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. The sequence and analysis of duplication-rich human chromosome 16. Martin J, et al. Nature, 2004 Dec 23. PMID 15616553
    2. Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer. Vichas A, et al. Nat Commun, 2021 Aug 9. PMID 34373451, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    nuclear pore complex-interacting protein family member B9
    Names
    Nuclear pore complex-interacting protein family member B9

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001287250.3 → NP_001274179.1  nuclear pore complex-interacting protein family member B9

      See identical proteins and their annotated locations for NP_001274179.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC145285
      UniProtKB/Swiss-Prot
      F8VUA1, F8W1W9
      UniProtKB/TrEMBL
      B2RXF8
      Related
      ENSP00000350444.4, ENST00000357796.8
      Conserved Domains (3) summary
      TIGR02794
      Location:360 → 425
      tolA_full; TolA protein
      pfam06409
      Location:41 → 301
      NPIP; Nuclear pore complex interacting protein (NPIP)
      cl17068
      Location:1 → 41
      AFD_class_I; Adenylate forming domain, Class I superfamily

    RNA

    1. NR_176858.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC145285
      Related
      ENST00000550983.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      28751787..28772864
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011545693.4 → XP_011543995.1  nuclear pore complex-interacting protein family member B9 isoform X2

      UniProtKB/TrEMBL
      I3L0I5
      Conserved Domains (3) summary
      TIGR02794
      Location:389 → 454
      tolA_full; TolA protein
      pfam06409
      Location:70 → 330
      NPIP; Nuclear pore complex interacting protein (NPIP)
      cl17068
      Location:1 → 41
      AFD_class_I; Adenylate forming domain, Class I superfamily

    2. XM_017022825.3 → XP_016878314.1  nuclear pore complex-interacting protein family member B9 isoform X4

      UniProtKB/TrEMBL
      I3L0I5

    3. XM_047433478.1 → XP_047289434.1  nuclear pore complex-interacting protein family member B9 isoform X6

      UniProtKB/TrEMBL
      A0A494C1T1

    4. XM_017022823.3 → XP_016878312.1  nuclear pore complex-interacting protein family member B9 isoform X3

      UniProtKB/TrEMBL
      I3L0I5

    5. XM_047433477.1 → XP_047289433.1  nuclear pore complex-interacting protein family member B9 isoform X5

      UniProtKB/TrEMBL
      I3L0I5

    6. XM_047433479.1 → XP_047289435.1  nuclear pore complex-interacting protein family member B9 isoform X8

      UniProtKB/TrEMBL
      A0A494C1T1

    7. XM_017022821.3 → XP_016878310.1  nuclear pore complex-interacting protein family member B9 isoform X1

      UniProtKB/TrEMBL
      I3L0I5

    8. XM_017022827.3 → XP_016878316.1  nuclear pore complex-interacting protein family member B9 isoform X7

    9. XM_047433481.1 → XP_047289437.1  nuclear pore complex-interacting protein family member B9 isoform X10

    10. XM_047433480.1 → XP_047289436.1  nuclear pore complex-interacting protein family member B9 isoform X9

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      29016081..29053452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054379339.1 → XP_054235314.1  nuclear pore complex-interacting protein family member B9 isoform X11

      UniProtKB/TrEMBL
      B2RXF8

    2. XM_054379342.1 → XP_054235317.1  nuclear pore complex-interacting protein family member B9 isoform X12

      UniProtKB/TrEMBL
      B2RXF8

    3. XM_054379338.1 → XP_054235313.1  nuclear pore complex-interacting protein family member B9 isoform X11

      UniProtKB/TrEMBL
      B2RXF8

    4. XM_054379344.1 → XP_054235319.1  nuclear pore complex-interacting protein family member B9 isoform X13

      UniProtKB/TrEMBL
      I3L0I5

    5. XM_054379337.1 → XP_054235312.1  nuclear pore complex-interacting protein family member B9 isoform X11

      UniProtKB/TrEMBL
      B2RXF8

    6. XM_054379340.1 → XP_054235315.1  nuclear pore complex-interacting protein family member B9 isoform X4

      UniProtKB/TrEMBL
      I3L0I5

    7. XM_054379345.1 → XP_054235320.1  nuclear pore complex-interacting protein family member B9 isoform X6

      UniProtKB/TrEMBL
      O75199

    8. XM_054379341.1 → XP_054235316.1  nuclear pore complex-interacting protein family member B9 isoform X4

      UniProtKB/TrEMBL
      I3L0I5

    9. XM_054379343.1 → XP_054235318.1  nuclear pore complex-interacting protein family member B9 isoform X5

      UniProtKB/TrEMBL
      I3L0I5

    10. XM_054379346.1 → XP_054235321.1  nuclear pore complex-interacting protein family member B9 isoform X10

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001287251.3: Suppressed sequence

      Description
      NM_001287251.3: This RefSeq was removed because currently there is support for the transcript but not for the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F8W1W9.2 GenPept UniProtKB/Swiss-Prot:F8W1W9

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