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    ZNF41 zinc finger protein 41 [ Homo sapiens (human) ]

    Gene ID: 7592, updated on 27-Nov-2024

    Summary

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    Official Symbol
    ZNF41provided by HGNC
    Official Full Name
    zinc finger protein 41provided by HGNC
    Primary source
    HGNC:HGNC:13107
    See related
    Ensembl:ENSG00000147124 MIM:314995; AllianceGenome:HGNC:13107
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MRX89
    Summary
    This gene encodes a protein that contains KRAB-A and KRAB-B domains multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. An initial study suggested that this gene may be associated with X-linked cognitive disability, but a later study has called this finding into question (PMID:23871722).[provided by RefSeq, Apr 2016]
    Expression
    Ubiquitous expression in thyroid (RPKM 3.3), heart (RPKM 2.6) and 25 other tissues See more
    Orthologs
    all
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    Genomic context

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    See ZNF41 in Genome Data Viewer
    Location:
    Xp11.3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (47445178..47483222, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (46855058..46893113, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (47304577..47342621, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene zinc finger protein 157 Neighboring gene UBX domain protein 4 pseudogene Neighboring gene nucleophosmin 1 pseudogene 49 Neighboring gene uncharacterized LOC124900499 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29593 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20804 Neighboring gene long intergenic non-protein coding RNA 1560 Neighboring gene uncharacterized LOC124905183 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:47372169-47372670 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:47372671-47373170 Neighboring gene MPRA-validated peak7378 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20805 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20806 Neighboring gene NUS1 pseudogene 1 Neighboring gene Sharpr-MPRA regulatory region 9461 Neighboring gene uncharacterized LOC124905184 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:47415445-47415946 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20807 Neighboring gene A-Raf proto-oncogene, serine/threonine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Isolation and expression analysis of a human zinc finger gene (ZNF41) located on the short arm of the X chromosome. Franzè A, et al. Genomics, 1991 Apr. PMID 2037297
    2. Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation. Shoichet SA, et al. Am J Hum Genet, 2003 Dec. PMID 14628291, Free PMC Article
    3. Clustered organization of Krüppel zinc-finger genes at Xp11.23, flanking a translocation breakpoint at OATL1: a physical map with locus assignments for ZNF21, ZNF41, ZNF81, and ELK1. Knight JC, et al. Genomics, 1994 May 1. PMID 8088786
    4. Coding region intron/exon organization, alternative splicing, and X-chromosome inactivation of the KRAB/FPB-domain-containing human zinc finger gene ZNF41. Rosati M, et al. Cytogenet Cell Genet, 1999. PMID 10449920
    5. Members of the zinc finger protein gene family sharing a conserved N-terminal module. Rosati M, et al. Nucleic Acids Res, 1991 Oct 25. PMID 1945843, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ZNF41 is critical for cognitive development
      Title: Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2012-10-24)

    ClinGen Genome Curation Page
    Haploinsufficency

    Little evidence for dosage pathogenicity (Last evaluated 2012-10-24)

    ClinGen Genome Curation PagePubMed

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC8941

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger protein 41

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_008238.1 RefSeqGene

      Range
      4725..42769
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001324139.2 → NP_001311068.1  zinc finger protein 41 isoform b

      Status: REVIEWED

      Source sequence(s)
      AK294858, AL590223, DA127531
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (3) summary
      COG5048
      Location:218 → 640
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:508 → 532
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001324140.2 → NP_001311069.1  zinc finger protein 41 isoform a

      Status: REVIEWED

      Source sequence(s)
      AL590223, BQ053634, DA127531
      Consensus CDS
      CCDS14279.1
      Conserved Domains (3) summary
      smart00349
      Location:27 → 87
      KRAB; krueppel associated box
      COG5048
      Location:304 → 726
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001324141.2 → NP_001311070.1  zinc finger protein 41 isoform b

      Status: REVIEWED

      Source sequence(s)
      AL590223, DA127531, DA567652
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (3) summary
      COG5048
      Location:218 → 640
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:508 → 532
      zf-H2C2_2; Zinc-finger double domain

    4. NM_001324142.2 → NP_001311071.1  zinc finger protein 41 isoform c

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (5) summary
      smart00349
      Location:29 → 89
      KRAB; krueppel associated box
      COG5048
      Location:306 → 728
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:415 → 435
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:29 → 68
      KRAB; KRAB box
      pfam13465
      Location:596 → 620
      zf-H2C2_2; Zinc-finger double domain

    5. NM_001324143.2 → NP_001311072.1  zinc finger protein 41 isoform b

      Status: REVIEWED

      Source sequence(s)
      AL590223, DA783869
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (3) summary
      COG5048
      Location:218 → 640
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:508 → 532
      zf-H2C2_2; Zinc-finger double domain

    6. NM_001324144.2 → NP_001311073.1  zinc finger protein 41 isoform a

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      Consensus CDS
      CCDS14279.1
      Related
      ENSP00000508254.1, ENST00000684689.1
      Conserved Domains (3) summary
      smart00349
      Location:27 → 87
      KRAB; krueppel associated box
      COG5048
      Location:304 → 726
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. NM_001324145.2 → NP_001311074.1  zinc finger protein 41 isoform b

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (3) summary
      COG5048
      Location:218 → 640
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:508 → 532
      zf-H2C2_2; Zinc-finger double domain

    8. NM_001324147.2 → NP_001311076.1  zinc finger protein 41 isoform a

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      Consensus CDS
      CCDS14279.1
      Conserved Domains (3) summary
      smart00349
      Location:27 → 87
      KRAB; krueppel associated box
      COG5048
      Location:304 → 726
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. NM_001324148.2 → NP_001311077.1  zinc finger protein 41 isoform c

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (5) summary
      smart00349
      Location:29 → 89
      KRAB; krueppel associated box
      COG5048
      Location:306 → 728
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:415 → 435
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:29 → 68
      KRAB; KRAB box
      pfam13465
      Location:596 → 620
      zf-H2C2_2; Zinc-finger double domain

    10. NM_001324149.2 → NP_001311078.1  zinc finger protein 41 isoform b

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (3) summary
      COG5048
      Location:218 → 640
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:508 → 532
      zf-H2C2_2; Zinc-finger double domain

    11. NM_001324150.2 → NP_001311079.1  zinc finger protein 41 isoform a

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      Consensus CDS
      CCDS14279.1
      Conserved Domains (3) summary
      smart00349
      Location:27 → 87
      KRAB; krueppel associated box
      COG5048
      Location:304 → 726
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]

    12. NM_001324151.2 → NP_001311080.1  zinc finger protein 41 isoform d

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (5) summary
      smart00349
      Location:37 → 97
      KRAB; krueppel associated box
      COG5048
      Location:314 → 736
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:423 → 443
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:37 → 76
      KRAB; KRAB box
      pfam13465
      Location:604 → 628
      zf-H2C2_2; Zinc-finger double domain

    13. NM_001324152.2 → NP_001311081.1  zinc finger protein 41 isoform b

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (3) summary
      COG5048
      Location:218 → 640
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:508 → 532
      zf-H2C2_2; Zinc-finger double domain

    14. NM_001324153.2 → NP_001311082.1  zinc finger protein 41 isoform d

      Status: REVIEWED

      Source sequence(s)
      AL590223, AL590283, Z84466
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (5) summary
      smart00349
      Location:37 → 97
      KRAB; krueppel associated box
      COG5048
      Location:314 → 736
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:423 → 443
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:37 → 76
      KRAB; KRAB box
      pfam13465
      Location:604 → 628
      zf-H2C2_2; Zinc-finger double domain

    15. NM_001324154.1 → NP_001311083.1  zinc finger protein 41 isoform e

      Status: REVIEWED

      Source sequence(s)
      AJ010020, AL590223, BC015023
      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    16. NM_001324155.1 → NP_001311084.1  zinc finger protein 41 isoform f

      Status: REVIEWED

      Source sequence(s)
      AJ010020, AJ010021, AL590223, BC015023
      UniProtKB/Swiss-Prot
      A8K1V6, B4DH01, P51814, Q96LE8, Q9UMC4, Q9UMV5, Q9UMV6, Q9UMV7, Q9UMV8, Q9UMV9, Q9UMW0, Q9UMW1
      Conserved Domains (6) summary
      smart00349
      Location:69 → 129
      KRAB; krueppel associated box
      COG5048
      Location:346 → 768
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:455 → 475
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:677 → 699
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:69 → 108
      KRAB; KRAB box
      pfam13465
      Location:636 → 660
      zf-H2C2_2; Zinc-finger double domain

    17. NM_001324156.1 → NP_001311085.1  zinc finger protein 41 isoform g

      Status: REVIEWED

      Source sequence(s)
      AJ010022, AL590223, BC015023
      UniProtKB/Swiss-Prot
      P51814

    18. NM_001324157.1 → NP_001311086.1  zinc finger protein 41 isoform h

      Status: REVIEWED

      Source sequence(s)
      AJ010023, AL590223, BC015023
      UniProtKB/Swiss-Prot
      P51814

    19. NM_007130.4 → NP_009061.1  zinc finger protein 41 isoform a

      See identical proteins and their annotated locations for NP_009061.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AK290021, AL590223, BC015023
      Consensus CDS
      CCDS14279.1
      Related
      ENSP00000315173.7, ENST00000313116.11
      Conserved Domains (3) summary
      smart00349
      Location:27 → 87
      KRAB; krueppel associated box
      COG5048
      Location:304 → 726
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]

    20. NM_153380.3 → NP_700359.1  zinc finger protein 41 isoform a

      See identical proteins and their annotated locations for NP_700359.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1.
      Source sequence(s)
      AL590223, BC015023
      Consensus CDS
      CCDS14279.1
      Related
      ENSP00000366265.4, ENST00000377065.8
      Conserved Domains (3) summary
      smart00349
      Location:27 → 87
      KRAB; krueppel associated box
      COG5048
      Location:304 → 726
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      47445178..47483222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047442482.1 → XP_047298438.1  zinc finger protein 41 isoform X4

    2. XM_047442478.1 → XP_047298434.1  zinc finger protein 41 isoform X3

    3. XM_017029814.3 → XP_016885303.1  zinc finger protein 41 isoform X1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    4. XM_047442476.1 → XP_047298432.1  zinc finger protein 41 isoform X3

    5. XM_047442472.1 → XP_047298428.1  zinc finger protein 41 isoform X2

    6. XM_017029811.3 → XP_016885300.1  zinc finger protein 41 isoform X1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    7. XM_017029810.3 → XP_016885299.1  zinc finger protein 41 isoform X1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    8. XM_006724550.4 → XP_006724613.1  zinc finger protein 41 isoform X1

      See identical proteins and their annotated locations for XP_006724613.1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    9. XM_047442483.1 → XP_047298439.1  zinc finger protein 41 isoform X5

    10. XM_047442481.1 → XP_047298437.1  zinc finger protein 41 isoform X4

    11. XM_047442477.1 → XP_047298433.1  zinc finger protein 41 isoform X3

    12. XM_047442473.1 → XP_047298429.1  zinc finger protein 41 isoform X2

    13. XM_017029815.2 → XP_016885304.1  zinc finger protein 41 isoform X1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    14. XM_047442475.1 → XP_047298431.1  zinc finger protein 41 isoform X3

    15. XM_006724555.4 → XP_006724618.1  zinc finger protein 41 isoform X2

      See identical proteins and their annotated locations for XP_006724618.1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (5) summary
      smart00349
      Location:37 → 97
      KRAB; krueppel associated box
      COG5048
      Location:314 → 736
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:423 → 443
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:37 → 76
      KRAB; KRAB box
      pfam13465
      Location:604 → 628
      zf-H2C2_2; Zinc-finger double domain

    16. XM_017029812.2 → XP_016885301.1  zinc finger protein 41 isoform X1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    17. XM_047442484.1 → XP_047298440.1  zinc finger protein 41 isoform X5

    18. XM_017029817.2 → XP_016885306.1  zinc finger protein 41 isoform X4

      Conserved Domains (3) summary
      smart00349
      Location:27 → 87
      KRAB; krueppel associated box
      COG5048
      Location:304 → 726
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413 → 433
      ZF_C2H2; C2H2 Zn finger [structural motif]

    19. XM_047442480.1 → XP_047298436.1  zinc finger protein 41 isoform X3

    20. XM_017029816.2 → XP_016885305.1  zinc finger protein 41 isoform X2

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (5) summary
      smart00349
      Location:37 → 97
      KRAB; krueppel associated box
      COG5048
      Location:314 → 736
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:423 → 443
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:37 → 76
      KRAB; KRAB box
      pfam13465
      Location:604 → 628
      zf-H2C2_2; Zinc-finger double domain

    21. XM_047442471.1 → XP_047298427.1  zinc finger protein 41 isoform X1

    22. XM_047442479.1 → XP_047298435.1  zinc finger protein 41 isoform X3

    23. XM_047442474.1 → XP_047298430.1  zinc finger protein 41 isoform X2

    24. XM_017029813.2 → XP_016885302.1  zinc finger protein 41 isoform X1

      UniProtKB/Swiss-Prot
      P51814
      Conserved Domains (6) summary
      smart00349
      Location:61 → 121
      KRAB; krueppel associated box
      COG5048
      Location:338 → 760
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:447 → 467
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 691
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:61 → 100
      KRAB; KRAB box
      pfam13465
      Location:628 → 652
      zf-H2C2_2; Zinc-finger double domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      46855058..46893113 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054327799.1 → XP_054183774.1  zinc finger protein 41 isoform X4

    2. XM_054327795.1 → XP_054183770.1  zinc finger protein 41 isoform X3

    3. XM_054327782.1 → XP_054183757.1  zinc finger protein 41 isoform X1

    4. XM_054327793.1 → XP_054183768.1  zinc finger protein 41 isoform X3

    5. XM_054327788.1 → XP_054183763.1  zinc finger protein 41 isoform X2

    6. XM_054327781.1 → XP_054183756.1  zinc finger protein 41 isoform X1

    7. XM_054327783.1 → XP_054183758.1  zinc finger protein 41 isoform X1

    8. XM_054327779.1 → XP_054183754.1  zinc finger protein 41 isoform X1

    9. XM_054327801.1 → XP_054183776.1  zinc finger protein 41 isoform X5

    10. XM_054327798.1 → XP_054183773.1  zinc finger protein 41 isoform X4

    11. XM_054327794.1 → XP_054183769.1  zinc finger protein 41 isoform X3

    12. XM_054327789.1 → XP_054183764.1  zinc finger protein 41 isoform X2

    13. XM_054327785.1 → XP_054183760.1  zinc finger protein 41 isoform X1

    14. XM_054327792.1 → XP_054183767.1  zinc finger protein 41 isoform X3

    15. XM_054327787.1 → XP_054183762.1  zinc finger protein 41 isoform X2

    16. XM_054327780.1 → XP_054183755.1  zinc finger protein 41 isoform X1

    17. XM_054327802.1 → XP_054183777.1  zinc finger protein 41 isoform X5

    18. XM_054327800.1 → XP_054183775.1  zinc finger protein 41 isoform X4

    19. XM_054327797.1 → XP_054183772.1  zinc finger protein 41 isoform X3

    20. XM_054327791.1 → XP_054183766.1  zinc finger protein 41 isoform X2

    21. XM_054327786.1 → XP_054183761.1  zinc finger protein 41 isoform X1

    22. XM_054327796.1 → XP_054183771.1  zinc finger protein 41 isoform X3

    23. XM_054327790.1 → XP_054183765.1  zinc finger protein 41 isoform X2

    24. XM_054327784.1 → XP_054183759.1  zinc finger protein 41 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P51814.2 GenPept UniProtKB/Swiss-Prot:P51814

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