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    SPATA19 spermatogenesis associated 19 [ Homo sapiens (human) ]

    Gene ID: 219938, updated on 27-Nov-2024

    Summary

    Official Symbol
    SPATA19provided by HGNC
    Official Full Name
    spermatogenesis associated 19provided by HGNC
    Primary source
    HGNC:HGNC:30614
    See related
    Ensembl:ENSG00000166118 MIM:609805; AllianceGenome:HGNC:30614
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CT132; SPAS1; spergen1
    Summary
    Predicted to be involved in sperm mitochondrion organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis (RPKM 27.4) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SPATA19 in Genome Data Viewer
    Location:
    11q25
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (133835930..133845513, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (133878224..133887807, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (133710526..133715408, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene opioid binding protein/cell adhesion molecule like Neighboring gene small nucleolar RNA U13 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:133367412-133367912 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:133367913-133368413 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4087 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133378571-133379070 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:133380000-133380899 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133411065-133411636 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133415514-133416432 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133424165-133424756 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133424757-133425347 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:133440092-133441291 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133498537-133499043 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133499044-133499549 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133511071-133511692 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133590113-133591005 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133600941-133601440 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133616212-133617180 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133657715-133658245 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr11:133672578-133673777 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr11:133678028-133678694 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133678695-133679361 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133679362-133680028 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133712096-133712638 Neighboring gene long intergenic non-protein coding RNA 2743 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:133724195-133725394 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133764343-133765238 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133765239-133766134 Neighboring gene calponin 2 pseudogene Neighboring gene microRNA 4697 Neighboring gene immunoglobulin superfamily member 9B

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ25851

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sperm mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sperm mitochondrion organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion HTP PubMed 
    located_in sperm flagellum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in sperm midpiece IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm midpiece ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    spermatogenesis-associated protein 19, mitochondrial
    Names
    cancer/testis antigen 132
    spergen-1
    spermatogenic cell-specific gene 1 protein
    spermatogenic specific-gene1
    testis secretory sperm-binding protein Li 243mP

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291992.2NP_001278921.1  spermatogenesis-associated protein 19, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001278921.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK098717, AP001979, BX096445
      Consensus CDS
      CCDS8493.1
      UniProtKB/Swiss-Prot
      Q7Z5L4, Q8N7A9
      UniProtKB/TrEMBL
      A0A140VKB6
      Related
      ENSP00000435248.1, ENST00000532889.1
      Conserved Domains (1) summary
      pfam15212
      Location:25167
      SPATA19; Spermatogenesis-associated protein 19, mitochondrial
    2. NM_174927.3NP_777587.1  spermatogenesis-associated protein 19, mitochondrial precursor

      See identical proteins and their annotated locations for NP_777587.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AP001979, BC058039, BX096445
      Consensus CDS
      CCDS8493.1
      UniProtKB/Swiss-Prot
      Q7Z5L4, Q8N7A9
      UniProtKB/TrEMBL
      A0A140VKB6
      Related
      ENSP00000299140.3, ENST00000299140.8
      Conserved Domains (1) summary
      pfam15212
      Location:25167
      SPATA19; Spermatogenesis-associated protein 19, mitochondrial

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      133835930..133845513 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_947807.2 RNA Sequence

    2. XR_947806.2 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      133878224..133887807 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_008488362.1 RNA Sequence

    2. XR_008488361.1 RNA Sequence