NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_042130.2 RefSeqGene
- Range
-
5154..154190
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1338
mRNA and Protein(s)
-
NM_001258392.3 → NP_001245321.1 mitochondrial disaggregase isoform 2
See identical proteins and their annotated locations for NP_001245321.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AK023214, AP000593, BU848809, DC396265
- Consensus CDS
-
CCDS58154.1
- UniProtKB/TrEMBL
-
A0A2U3TZY2
- Related
- ENSP00000441518.1, ENST00000538039.6
- Conserved Domains (7) summary
-
- smart01086
Location:545 → 630
- ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
- smart00382
Location:343 → 480
- AAA; ATPases associated with a variety of cellular activities
- cd00204
Location:137 → 285
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam07724
Location:346 → 534
- AAA_2; AAA domain (Cdc48 subfamily)
- pfam12796
Location:138 → 266
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:137 → 164
- ANK; ANK repeat [structural motif]
- cl21455
Location:309 → 371
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001258393.3 → NP_001245322.1 mitochondrial disaggregase isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks two in-frame exons in the 5' coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AK302006, AP000593, BC006404, DC396265
- Consensus CDS
-
CCDS58153.1
- UniProtKB/TrEMBL
-
A0A2U3TZY2
- Related
- ENSP00000340385.5, ENST00000340729.9
- Conserved Domains (7) summary
-
- smart01086
Location:516 → 601
- ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
- smart00382
Location:314 → 451
- AAA; ATPases associated with a variety of cellular activities
- cd00204
Location:137 → 256
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam07724
Location:317 → 505
- AAA_2; AAA domain (Cdc48 subfamily)
- pfam12796
Location:138 → 237
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:137 → 168
- ANK; ANK repeat [structural motif]
- cl21455
Location:280 → 342
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_001258394.3 → NP_001245323.1 mitochondrial disaggregase isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and contains an alternate exon in the 5' coding region that results in initiation of translation at an alternate start codon and a novel 5' coding region compared to variant 1. The encoded isoform (4) is shorter than and has a distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AK302069, AP000593, BC006404, DC396265
- UniProtKB/Swiss-Prot
-
Q9H078
- Conserved Domains (7) summary
-
- smart01086
Location:530 → 615
- ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
- smart00382
Location:328 → 465
- AAA; ATPases associated with a variety of cellular activities
- cd00204
Location:108 → 270
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam07724
Location:331 → 519
- AAA_2; AAA domain (Cdc48 subfamily)
- pfam13857
Location:208 → 261
- Ank_5; Ankyrin repeats (many copies)
- sd00045
Location:121 → 152
- ANK; ANK repeat [structural motif]
- cl21455
Location:294 → 356
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
NM_030813.6 → NP_110440.1 mitochondrial disaggregase isoform 1
See identical proteins and their annotated locations for NP_110440.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AP000593, BC006404, DC396265
- Consensus CDS
-
CCDS8215.1
- UniProtKB/Swiss-Prot
- B4DXJ7, B4DXP7, B4DXW4, E7EWN6, F8W7P6, Q8ND11, Q9H078, Q9H8Y0
- UniProtKB/TrEMBL
- A0A140VK11, A0A2U3TZY2
- Related
- ENSP00000294053.3, ENST00000294053.9
- Conserved Domains (4) summary
-
- COG0542
Location:339 → 655
- ClpA; ATP-dependent Clp protease ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones]
- cd00204
Location:137 → 315
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- sd00045
Location:137 → 164
- ANK; ANK repeat [structural motif]
- cl27362
Location:78 → 211
- MCR_beta_N; Methyl-coenzyme M reductase beta subunit, N-terminal domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000011.10 Reference GRCh38.p14 Primary Assembly
- Range
-
72285495..72434531 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005274320.2 → XP_005274377.1 mitochondrial disaggregase isoform X1
- UniProtKB/TrEMBL
-
A0A2U3TZY2
- Conserved Domains (7) summary
-
- smart01086
Location:546 → 631
- ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein
- smart00382
Location:344 → 481
- AAA; ATPases associated with a variety of cellular activities
- cd00204
Location:137 → 286
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam07724
Location:347 → 535
- AAA_2; AAA domain (Cdc48 subfamily)
- pfam13857
Location:224 → 277
- Ank_5; Ankyrin repeats (many copies)
- sd00045
Location:237 → 267
- ANK; ANK repeat [structural motif]
- cl21455
Location:310 → 372
- P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
-
XM_047427655.1 → XP_047283611.1 mitochondrial disaggregase isoform X2
-
XM_047427656.1 → XP_047283612.1 mitochondrial disaggregase isoform X3
-
XM_011545289.3 → XP_011543591.1 mitochondrial disaggregase isoform X4
- UniProtKB/TrEMBL
-
A0A2R8Y6R5
- Conserved Domains (3) summary
-
- cd00204
Location:137 → 315
- ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
- pfam12796
Location:138 → 296
- Ank_2; Ankyrin repeats (3 copies)
- sd00045
Location:137 → 164
- ANK; ANK repeat [structural motif]
Alternate T2T-CHM13v2.0
Genomic
-
NC_060935.1 Alternate T2T-CHM13v2.0
- Range
-
72211988..72361006 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054370076.1 → XP_054226051.1 mitochondrial disaggregase isoform X1
- UniProtKB/TrEMBL
-
A0A2U3TZY2
-
XM_054370077.1 → XP_054226052.1 mitochondrial disaggregase isoform X2
-
XM_054370078.1 → XP_054226053.1 mitochondrial disaggregase isoform X3
-
XM_054370079.1 → XP_054226054.1 mitochondrial disaggregase isoform X4
- UniProtKB/TrEMBL
-
A0A2R8Y6R5