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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_031981.1 RefSeqGene
- Range
-
4991..21206
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001004105.3 → NP_001004105.1 G protein-coupled receptor kinase 6 isoform C
See identical proteins and their annotated locations for NP_001004105.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains an alternate 3' terminal exon, compared to variant 2, resulting in a shorter isoform (C) with a distinct C-terminus compared to isoform B.
- Source sequence(s)
-
AC145098, AF040752, BC009277, BI258860
- Consensus CDS
-
CCDS43406.1
- UniProtKB/TrEMBL
-
Q96AD6
- Related
- ENSP00000348230.5, ENST00000355958.9
- Conserved Domains (3) summary
-
- smart00220
Location:186 → 448
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd05630
Location:185 → 469
- STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
- cl02565
Location:35 → 179
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
NM_001004106.3 → NP_001004106.1 G protein-coupled receptor kinase 6 isoform A
See identical proteins and their annotated locations for NP_001004106.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) uses an alternate acceptor splice site in the last exon, compared to variant 2, resulting in a shorter isoform (A) compared to isoform B.
- Source sequence(s)
-
AC145098, BC009277, BI258860
- Consensus CDS
-
CCDS34303.1
- UniProtKB/Swiss-Prot
- O60541, P43250, Q13652
- UniProtKB/TrEMBL
-
F8W9W2
- Related
- ENSP00000347655.5, ENST00000355472.10
- Conserved Domains (2) summary
-
- cd05630
Location:185 → 469
- STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
- cl02565
Location:35 → 179
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
NM_001364164.2 → NP_001351093.1 G protein-coupled receptor kinase 6 isoform D
Status: REVIEWED
- Source sequence(s)
-
AC145098
- Conserved Domains (1) summary
-
- cl21453
Location:1 → 259
- PKc_like; Protein Kinases, catalytic domain
-
NM_002082.4 → NP_002073.2 G protein-coupled receptor kinase 6 isoform B
See identical proteins and their annotated locations for NP_002073.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (B).
- Source sequence(s)
-
AC145098, AF040751, BC009277, BI258860
- UniProtKB/TrEMBL
-
Q96AD6
- Conserved Domains (3) summary
-
- smart00220
Location:186 → 448
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd05630
Location:185 → 469
- STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
- cl02565
Location:35 → 179
- RGS; Regulator of G protein signaling (RGS) domain superfamily
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000005.10 Reference GRCh38.p14 Primary Assembly
- Range
-
177425523..177442891
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047417126.1 → XP_047273082.1 G protein-coupled receptor kinase 6 isoform X3
- UniProtKB/TrEMBL
-
F8W9W2
-
XM_006714859.3 → XP_006714922.1 G protein-coupled receptor kinase 6 isoform X2
- UniProtKB/TrEMBL
-
Q96AD6
- Conserved Domains (3) summary
-
- smart00220
Location:154 → 416
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd05630
Location:153 → 437
- STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
- cl02565
Location:3 → 147
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
XM_006714858.4 → XP_006714921.1 G protein-coupled receptor kinase 6 isoform X1
See identical proteins and their annotated locations for XP_006714921.1
- UniProtKB/TrEMBL
- B3KPS5, Q96AD6
- Conserved Domains (3) summary
-
- smart00220
Location:156 → 418
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd05630
Location:155 → 439
- STKc_GRK6; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 6
- cl02565
Location:20 → 149
- RGS; Regulator of G protein signaling (RGS) domain superfamily
-
XM_011534538.2 → XP_011532840.1 G protein-coupled receptor kinase 6 isoform X4
- Conserved Domains (2) summary
-
- smart00220
Location:1 → 183
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl21453
Location:1 → 204
- PKc_like; Protein Kinases, catalytic domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060929.1 Alternate T2T-CHM13v2.0
- Range
-
177968774..177986142
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054352461.1 → XP_054208436.1 G protein-coupled receptor kinase 6 isoform X3
- UniProtKB/TrEMBL
-
F8W9W2
-
XM_054352460.1 → XP_054208435.1 G protein-coupled receptor kinase 6 isoform X2
- UniProtKB/TrEMBL
-
Q96AD6
-
XM_054352459.1 → XP_054208434.1 G protein-coupled receptor kinase 6 isoform X1
- UniProtKB/TrEMBL
- B3KPS5, Q96AD6
-
XM_054352462.1 → XP_054208437.1 G protein-coupled receptor kinase 6 isoform X4