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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001135729.2 → NP_001129201.1 target of Myb1 membrane trafficking protein isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains a different 5' terminal exon and uses an alternate donor splice site at the penultimate exon compared to transcript variant 1. This results in translation initiation from a downstream AUG and an isoform (3) with a shorter N-terminus compared to isoform 1.
- Source sequence(s)
-
AJ006973, AK097066, AK293694
- Consensus CDS
-
CCDS46698.1
- UniProtKB/TrEMBL
-
B4DKQ5
- Related
- ENSP00000398876.1, ENST00000447733.5
- Conserved Domains (2) summary
-
- cd14236
Location:181 → 275
- GAT_TOM1; GAT domain found in target of Myb protein 1 (Tom1)
- cl02544
Location:1 → 119
- VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
-
NM_001135730.2 → NP_001129202.1 target of Myb1 membrane trafficking protein isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) is missing an in-frame coding exon compared to transcript variant 1, resulting in a shorter isoform (4) lacking an internal 45 aa segment compared to isoform 1.
- Source sequence(s)
-
AJ006973, AK097066, DC297234
- Consensus CDS
-
CCDS46697.1
- UniProtKB/TrEMBL
-
B4DKQ5
- Related
- ENSP00000394924.1, ENST00000425375.5
- Conserved Domains (2) summary
-
- cd14236
Location:169 → 263
- GAT_TOM1; GAT domain found in target of Myb protein 1 (Tom1)
- cl02544
Location:12 → 123
- VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
-
NM_001135732.2 → NP_001129204.1 target of Myb1 membrane trafficking protein isoform 2
See identical proteins and their annotated locations for NP_001129204.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate donor splice site at the penultimate exon compared to transcript variant 1, resulting in an isoform (2) with one extra aa compared to isoform 1.
- Source sequence(s)
-
BC046151, DC297234
- Consensus CDS
-
CCDS46696.1
- UniProtKB/TrEMBL
-
B4DKQ5
- Related
- ENSP00000413697.1, ENST00000411850.5
- Conserved Domains (2) summary
-
- cd03565
Location:12 → 152
- VHS_Tom1; VHS domain family, Tom1 subfamily; The VHS domain is an essential part of Tom1 (Target of myb1 - retroviral oncogene) protein. The VHS domain has a superhelical structure similar to the structure of the ARM repeats and is present at the very N-termini of ...
- cd14236
Location:214 → 308
- GAT_TOM1; GAT domain found in target of Myb protein 1 (Tom1)
-
NM_005488.3 → NP_005479.1 target of Myb1 membrane trafficking protein isoform 1
See identical proteins and their annotated locations for NP_005479.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the most predominant transcript and encodes isoform 1.
- Source sequence(s)
-
AJ006973, AK097066, DC297234
- Consensus CDS
-
CCDS13913.1
- UniProtKB/Swiss-Prot
- B4DEL9, B4DNA1, O60784, Q5TIJ6, Q86X74
- UniProtKB/TrEMBL
-
B4DKQ5
- Related
- ENSP00000394466.2, ENST00000449058.7
- Conserved Domains (2) summary
-
- cd03565
Location:12 → 152
- VHS_Tom1; VHS domain family, Tom1 subfamily; The VHS domain is an essential part of Tom1 (Target of myb1 - retroviral oncogene) protein. The VHS domain has a superhelical structure similar to the structure of the ARM repeats and is present at the very N-termini of ...
- cd14236
Location:214 → 308
- GAT_TOM1; GAT domain found in target of Myb protein 1 (Tom1)
RNA
-
NR_024194.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses an alternate acceptor splice site at one of the coding exons compared to transcript variant 1. This results in a frame-shift and premature translation termination, rendering the transcript susceptible to nonsense mediated mRNA decay (NMD). This variant is sufficiently abundant to represent as a RefSeq record, however, the predicted protein is not represented because it is significantly truncated.
- Source sequence(s)
-
AK097066, AK296670, DC297234
- Related
-
ENST00000424387.5
-
NR_024195.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) is missing an internal coding exon and uses an alternate acceptor splice site at another coding exon compared to transcript variant 1. This results in a frame-shift and premature translation termination, rendering the transcript susceptible to nonsense mediated mRNA decay (NMD). This variant is sufficiently abundant to represent as a RefSeq record, however, the predicted protein is not represented because it is significantly truncated.
- Source sequence(s)
-
AJ006973, AK097066, AK295918, DC297234
-
NR_156428.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) is missing an internal coding exon compared to transcript variant 1. This results in a frame-shift and premature translation termination, rendering the transcript susceptible to nonsense mediated mRNA decay (NMD). This variant is sufficiently abundant to represent as a RefSeq record, however, the predicted protein is not represented because it is significantly truncated.
- Source sequence(s)
-
AL008635, Z82244
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000022.11 Reference GRCh38.p14 Primary Assembly
- Range
-
35299275..35347973
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047441068.1 → XP_047297024.1 target of Myb1 membrane trafficking protein isoform X1
- UniProtKB/TrEMBL
-
B4DKQ5
-
XM_047441069.1 → XP_047297025.1 target of Myb1 membrane trafficking protein isoform X2
- UniProtKB/TrEMBL
-
B4DKQ5
-
XM_011529820.3 → XP_011528122.1 target of Myb1 membrane trafficking protein isoform X4
- Conserved Domains (1) summary
-
- cd14236
Location:62 → 156
- GAT_TOM1; GAT domain found in target of Myb protein 1 (Tom1)
-
XM_011529818.3 → XP_011528120.1 target of Myb1 membrane trafficking protein isoform X3
- UniProtKB/TrEMBL
-
B4DJ44
- Conserved Domains (2) summary
-
- cd14236
Location:147 → 241
- GAT_TOM1; GAT domain found in target of Myb protein 1 (Tom1)
- cl02544
Location:1 → 85
- VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
-
XM_047441070.1 → XP_047297026.1 target of Myb1 membrane trafficking protein isoform X5
Alternate T2T-CHM13v2.0
Genomic
-
NC_060946.1 Alternate T2T-CHM13v2.0
- Range
-
35757154..35805980
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054324975.1 → XP_054180950.1 target of Myb1 membrane trafficking protein isoform X1
- UniProtKB/TrEMBL
-
B4DKQ5
-
XM_054324976.1 → XP_054180951.1 target of Myb1 membrane trafficking protein isoform X2
- UniProtKB/TrEMBL
-
B4DKQ5
-
XM_054324978.1 → XP_054180953.1 target of Myb1 membrane trafficking protein isoform X4
-
XM_054324977.1 → XP_054180952.1 target of Myb1 membrane trafficking protein isoform X3
- UniProtKB/TrEMBL
-
B4DJ44
-
XM_054324979.1 → XP_054180954.1 target of Myb1 membrane trafficking protein isoform X5