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    Anapc13 anaphase promoting complex subunit 13 [ Mus musculus (house mouse) ]

    Gene ID: 69010, updated on 27-Nov-2024

    Summary

    Official Symbol
    Anapc13provided by MGI
    Official Full Name
    anaphase promoting complex subunit 13provided by MGI
    Primary source
    MGI:MGI:1916260
    See related
    Ensembl:ENSMUSG00000035048 AllianceGenome:MGI:1916260
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SWM1; APC13; 1810004D07Rik
    Summary
    Predicted to be involved in anaphase-promoting complex-dependent catabolic process and protein polyubiquitination. Predicted to be part of anaphase-promoting complex. Is expressed in several structures, including gallbladder; genitourinary system; gut gland; nervous system; and retina. Orthologous to human ANAPC13 (anaphase promoting complex subunit 13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 56.9), placenta adult (RPKM 44.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Anapc13 in Genome Data Viewer
    Location:
    9 F1; 9 54.64 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (102503495..102511443)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (102626296..102634244)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene karyopherin alpha 7 (importin alpha 8) pseudogene Neighboring gene predicted gene 29387 Neighboring gene WD repeat domain 85 pseudogene Neighboring gene centrosomal protein 63 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:102528825-102529014 Neighboring gene VISTA enhancer mm1302 Neighboring gene STARR-seq mESC enhancer starr_25068 Neighboring gene predicted gene, 46150 Neighboring gene STARR-seq mESC enhancer starr_25069 Neighboring gene angiomotin-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in anaphase-promoting complex-dependent catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein K11-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K11-linked ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K48-linked ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein branched polyubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of anaphase-promoting complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of anaphase-promoting complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    anaphase-promoting complex subunit 13
    Names
    cyclosome subunit 13
    cylosome subunit 13

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181394.3NP_852059.1  anaphase-promoting complex subunit 13

      See identical proteins and their annotated locations for NP_852059.1

      Status: VALIDATED

      Source sequence(s)
      BC028526, BY347589
      Consensus CDS
      CCDS40744.1
      UniProtKB/Swiss-Prot
      Q8R034
      Related
      ENSMUSP00000140967.2, ENSMUST00000190279.7
      Conserved Domains (1) summary
      pfam05839
      Location:174
      Apc13p; Apc13p protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      102503495..102511443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511807.5XP_006511870.1  anaphase-promoting complex subunit 13 isoform X1

      See identical proteins and their annotated locations for XP_006511870.1

      UniProtKB/Swiss-Prot
      Q8R034
      Related
      ENSMUSP00000139762.2, ENSMUST00000186693.2
      Conserved Domains (1) summary
      pfam05839
      Location:174
      Apc13p; Apc13p protein
    2. XM_006511806.4XP_006511869.1  anaphase-promoting complex subunit 13 isoform X1

      See identical proteins and their annotated locations for XP_006511869.1

      UniProtKB/Swiss-Prot
      Q8R034
      Related
      ENSMUSP00000140325.2, ENSMUST00000188398.7
      Conserved Domains (1) summary
      pfam05839
      Location:174
      Apc13p; Apc13p protein
    3. XM_036155234.1XP_036011127.1  anaphase-promoting complex subunit 13 isoform X1

      UniProtKB/Swiss-Prot
      Q8R034
      Conserved Domains (1) summary
      pfam05839
      Location:174
      Apc13p; Apc13p protein