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    Prss52 serine protease 52 [ Mus musculus (house mouse) ]

    Gene ID: 73382, updated on 27-Nov-2024

    Summary

    Official Symbol
    Prss52provided by MGI
    Official Full Name
    serine protease 52provided by MGI
    Primary source
    MGI:MGI:1920632
    See related
    Ensembl:ENSMUSG00000021966 AllianceGenome:MGI:1920632
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tesp3; 1700049K14Rik
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Orthologous to human PRSS52P (serine protease 52, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 43.2) See more
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    Genomic context

    See Prss52 in Genome Data Viewer
    Location:
    14 D1; 14 33.35 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (64341772..64351200)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (64104323..64113751)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930471C04 gene Neighboring gene serine protease 55 Neighboring gene RIKEN cDNA 9630015K15 gene Neighboring gene serine protease 51 Neighboring gene methionine sulfoxide reductase A Neighboring gene predicted gene, 53862

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine protease 52
    Names
    protease, serine 52
    testicular serine protease 3
    testicular-specific serine protease 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028525.2NP_082801.2  serine protease 52 precursor

      See identical proteins and their annotated locations for NP_082801.2

      Status: PROVISIONAL

      Source sequence(s)
      BC049714
      Consensus CDS
      CCDS36953.1
      UniProtKB/Swiss-Prot
      A8C1Y0, Q80Y38, Q9D9M0
      Related
      ENSMUSP00000022537.6, ENSMUST00000022537.6
      Conserved Domains (2) summary
      smart00020
      Location:56282
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:56285
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      64341772..64351200
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)