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    Nt5dc1 5'-nucleotidase domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294456, updated on 9-Dec-2024

    Summary

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    Symbol
    Nt5dc1provided by RGD
    Full Name
    5'-nucleotidase domain containing 1provided by RGD
    Primary source
    RGD:1305214
    See related
    EnsemblRapid:ENSRNOG00000000546 AllianceGenome:RGD:1305214
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Nt5c2l1
    Summary
    Predicted to enable 5'-nucleotidase activity. Orthologous to human NT5DC1 (5'-nucleotidase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 120.5), Liver (RPKM 118.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nt5dc1 in Genome Data Viewer
    Location:
    20q12
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (39660707..39763647, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (38105677..38208613, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (41106990..41209765, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene TSPY-like 1 Neighboring gene TSPY-like 4 Neighboring gene collagen type X alpha 1 chain Neighboring gene uncharacterized LOC120098933 Neighboring gene uncharacterized LOC120098931 Neighboring gene fyn-related Src family tyrosine kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 5'-nucleotidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    5'-nucleotidase domain-containing protein 1
    Names
    5'-nucleotidase domain-containing protein 1-like
    5'-nucleotidase, cytosolic II-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106393.2 → NP_001099863.2  5'-nucleotidase domain-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      A0A9K3Y748, B1WC66, F7EPM6
      Related
      ENSRNOP00000000657.7, ENSRNOT00000000657.8
      Conserved Domains (1) summary
      cl21460
      Location:3 → 343
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      39660707..39763647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008772981.4 → XP_008771203.1  5'-nucleotidase domain-containing protein 1 isoform X1

      Related
      ENSRNOP00000110072.1, ENSRNOT00000121516.1
      Conserved Domains (1) summary
      cl17687
      Location:11 → 356
      5_nucleotid; 5' nucleotidase family

    2. XM_039098600.1 → XP_038954528.1  5'-nucleotidase domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A6KID0
      Conserved Domains (1) summary
      cl21460
      Location:2 → 122
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    3. XM_039098602.2 → XP_038954530.1  5'-nucleotidase domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I6AAF7
      Conserved Domains (1) summary
      cl21460
      Location:3 → 184
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    4. XM_039098604.2 → XP_038954532.1  5'-nucleotidase domain-containing protein 1 isoform X6

      Conserved Domains (1) summary
      cl21460
      Location:3 → 198
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    5. XM_039098601.2 → XP_038954529.1  5'-nucleotidase domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AAF7
      Conserved Domains (1) summary
      cl21460
      Location:3 → 185
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    6. XM_039098605.2 → XP_038954533.1  5'-nucleotidase domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8I6AAF7
      Conserved Domains (1) summary
      cl21460
      Location:3 → 191
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    7. XM_039098603.2 → XP_038954531.1  5'-nucleotidase domain-containing protein 1 isoform X5

      Conserved Domains (1) summary
      cl21460
      Location:3 → 199
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version

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